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sgt2 SGT2 family TPR repeat-containing protein [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542401, updated on 18-Sep-2024

Summary

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Official Symbol
sgt2
Official Full Name
SGT2 family TPR repeat-containing protein
Primary source
PomBase:SPAC1142.02c
Locus tag
SPOM_SPAC1142.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPAC17G6.19c
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Genomic context

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See sgt2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (3627675..3628955, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Rqc1 Neighboring gene ncRNA Neighboring gene DNA recombination mediator Swi2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Noc complex Noc2 family subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dynamic stability of Sgt2 enables selective and privileged client handover in a chaperone triad. Cho H, et al. Nat Commun, 2024 Jan 2. PMID 38167697, Free PMC Article
  2. Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions. Nie M, et al. J Biol Chem, 2012 Aug 24. PMID 22730331, Free PMC Article
  3. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
  4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
  5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables membrane insertase activity TAS
Traceable Author Statement
more info
 PubMed 
enables molecular adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in post-translational protein targeting to endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of TRC complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SGT2 family TPR repeat-containing protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3627675..3628955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001356124.2 → NP_001342950.1  SGT2 family TPR repeat-containing protein [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13797
    Conserved Domains (3) summary
    sd00006
    Location:83 → 111
    TPR; TPR repeat [structural motif]
    pfam16546
    Location:4 → 53
    SGTA_dimer; Homodimerisation domain of SGTA
    cl26005
    Location:59 → 165
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
Nucleotide Protein
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