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fin1 NIMA-like serine/threonine protein kinase Fin1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542237, updated on 18-Sep-2024

Summary

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Official Symbol
fin1
Official Full Name
NIMA-like serine/threonine protein kinase Fin1
Primary source
PomBase:SPAC19E9.02
Locus tag
SPOM_SPAC19E9.02
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See fin1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (1354221..1357184)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene cleavage and polyadenylation specificity factor complex subunit Rna14 Neighboring gene ncRNA Neighboring gene nucleoporin Nup40 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A NIMA homologue promotes chromatin condensation in fission yeast. Krien MJ, et al. J Cell Sci, 1998 Apr. PMID 9490640
  2. The fission yeast NIMA kinase Fin1p is required for spindle function and nuclear envelope integrity. Krien MJ, et al. EMBO J, 2002 Apr 2. PMID 11927555, Free PMC Article
  3. Recruitment of NIMA kinase shows that maturation of the S. pombe spindle-pole body occurs over consecutive cell cycles and reveals a role for NIMA in modulating SIN activity. Grallert A, et al. Genes Dev, 2004 May 1. PMID 15132994, Free PMC Article
  4. The S. pombe cytokinesis NDR kinase Sid2 activates Fin1 NIMA kinase to control mitotic commitment through Pom1/Wee1. Grallert A, et al. Nat Cell Biol, 2012 Jun 10. PMID 22684255, Free PMC Article
  5. Rad18 is required for DNA repair and checkpoint responses in fission yeast. Verkade HM, et al. Mol Biol Cell, 1999 Sep. PMID 10473635, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Sid2 activation midway through G2 phase promotes Fin1 phosphorylation and mitotic commitment throught pom1/Wee1 cell geometry network.
    Title: The S. pombe cytokinesis NDR kinase Sid2 activates Fin1 NIMA kinase to control mitotic commitment through Pom1/Wee1.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein serine/threonine/tyrosine kinase activity EXP
Inferred from Experiment
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromosome segregation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of septation initiation signaling EXP
Inferred from Experiment
more info
 PubMed 
involved_in nuclear envelope organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of G2/M transition of mitotic cell cycle EXP
Inferred from Experiment
more info
 PubMed 
involved_in positive regulation of G2/M transition of mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in mitotic spindle IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic spindle pole body HDA PubMed 
is_active_in mitotic spindle pole body IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nuclear envelope HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
NIMA-like serine/threonine protein kinase Fin1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1354221..1357184
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018735.3 → NP_593305.1  NIMA-like serine/threonine protein kinase Fin1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593305.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13839
    Conserved Domains (2) summary
    smart00220
    Location:4 → 281
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd08217
    Location:3 → 281
    STKc_Nek2; Catalytic domain of the Serine/Threonine Kinase, Never In Mitosis gene A (NIMA)-related kinase 2
Nucleotide Protein
Heading Accession and Version

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