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mst2 histone acetyltransferase Mst2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542170, updated on 18-Sep-2024

Summary

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Official Symbol
mst2
Official Full Name
histone acetyltransferase Mst2
Primary source
PomBase:SPAC17G8.13c
Locus tag
SPOM_SPAC17G8.13C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See mst2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (2363499..2366934, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene exocyst complex subunit Sec3 Neighboring gene protein kinase C (PKC)-like Pck1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression profiling of S. pombe acetyltransferase mutants identifies redundant pathways of gene regulation. Nugent RL, et al. BMC Genomics, 2010 Jan 22. PMID 20096118, Free PMC Article
  2. Rapid epigenetic adaptation to uncontrolled heterochromatin spreading. Wang J, et al. Elife, 2015 Mar 16. PMID 25774602, Free PMC Article
  3. Spt6 is required for heterochromatic silencing in the fission yeast Schizosaccharomyces pombe. Kiely CM, et al. Mol Cell Biol, 2011 Oct. PMID 21844224, Free PMC Article
  4. Distinct chromatin modulators regulate the formation of accessible and repressive chromatin at the fission yeast recombination hotspot ade6-M26. Hirota K, et al. Mol Biol Cell, 2008 Mar. PMID 18199689, Free PMC Article
  5. Schizosaccharomyces pombe mst2+ encodes a MYST family histone acetyltransferase that negatively regulates telomere silencing. Gómez EB, et al. Mol Cell Biol, 2005 Oct. PMID 16199868, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone H3K14 acetyltransferase activity TAS
Traceable Author Statement
more info
 PubMed 
enables histone acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in heterochromatin boundary formation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in heterochromatin formation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Mst2 histone acetyltransferase complex TAS
Traceable Author Statement
more info
 PubMed 
part_of NuA3a histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
histone acetyltransferase Mst2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2363499..2366934 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019167.3 → NP_593736.1  histone acetyltransferase Mst2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593736.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10325
    Conserved Domains (2) summary
    COG5027
    Location:1 → 370
    SAS2; Histone acetyltransferase (MYST family) [Chromatin structure and dynamics]
    cl17182
    Location:102 → 372
    NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
Nucleotide Protein
Heading Accession and Version

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