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rad57 DNA recombination mediator, RecA family ATPase Rad57/Rhp57 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542007, updated on 18-Sep-2024

Summary

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Official Symbol
rad57
Official Full Name
DNA recombination mediator, RecA family ATPase Rad57/Rhp57
Primary source
PomBase:SPAC20H4.07
Locus tag
SPOM_SPAC20H4.07
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
rhp57
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Genomic context

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See rad57 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (2123030..2124506)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Gpl1-Gih35-Wdr83 complex RNA-binding subunit Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene phosphatase activator Neighboring gene ncRNA Neighboring gene ATP-dependent RNA helicase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and characterization of the rlp1+, the novel Rad51 paralog in the fission yeast Schizosaccharomyces pombe. Khasanov FK, et al. DNA Repair (Amst), 2004 Oct 5. PMID 15336631
  2. A recombination repair gene of Schizosaccharomyces pombe, rhp57, is a functional homolog of the Saccharomyces cerevisiae RAD57 gene and is phylogenetically related to the human XRCC3 gene. Tsutsui Y, et al. Genetics, 2000 Apr. PMID 10747044, Free PMC Article
  3. The role of novel genes rrp1(+) and rrp2(+) in the repair of DNA damage in Schizosaccharomyces pombe. Dziadkowiec D, et al. DNA Repair (Amst), 2009 May 1. PMID 19185548
  4. Crossover invariance determined by partner choice for meiotic DNA break repair. Hyppa RW, et al. Cell, 2010 Jul 23. PMID 20655467, Free PMC Article
  5. Mus81-Eme1-dependent and -independent crossovers form in mitotic cells during double-strand break repair in Schizosaccharomyces pombe. Hope JC, et al. Mol Cell Biol, 2007 May. PMID 17353272, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. rqh1 plays a role late in HR following replication arrest and Rhp55/57 has a postsynaptic function
    Title: A postsynaptic role for Rhp55/57 that is responsible for cell death in Deltarqh1 mutants following replication arrest in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity NAS
Non-traceable Author Statement
more info
  
enables ATP-dependent DNA damage sensor activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent activity, acting on DNA IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA strand exchange activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in DNA recombinase assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA recombinase assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in DNA strand invasion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in double-strand break repair via homologous recombination IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in mating type switching IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of Rad51C-XRCC3 complex NAS
Non-traceable Author Statement
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in site of double-strand break IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
DNA recombination mediator, RecA family ATPase Rad57/Rhp57

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2123030..2124506
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019058.3 → NP_593627.1  DNA recombination mediator, RecA family ATPase Rad57/Rhp57 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593627.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9P7A6, Q9UUL2
    Conserved Domains (2) summary
    COG0468
    Location:32 → 354
    RecA; RecA/RadA recombinase [Replication, recombination and repair]
    cd01123
    Location:75 → 352
    Rad51_DMC1_radA; Rad51_DMC1_radA,B. This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal proteins radA and radB. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a ...
Nucleotide Protein
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