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set3 putative histone H3 lysine methyltransferase Set3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541899, updated on 18-Sep-2024

Summary

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Official Symbol
set3
Official Full Name
putative histone H3 lysine methyltransferase Set3
Primary source
PomBase:SPAC22E12.11c
Locus tag
SPOM_SPAC22E12.11C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See set3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (5039546..5042744, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene kexin Neighboring gene ncRNA Neighboring gene monooxygenase-ferredoxin fusion protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Arg Neighboring gene ribosome biogenesis protein rlp24

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Set3 contributes to heterochromatin integrity by promoting transcription of subunits of Clr4-Rik1-Cul4 histone methyltransferase complex in fission yeast. Yu Y, et al. Sci Rep, 2016 Aug 19. PMID 27538348, Free PMC Article
  2. Genome-wide screen of fission yeast mutants for sensitivity to 6-azauracil, an inhibitor of transcriptional elongation. Zhou H, et al. Yeast, 2015 Oct. PMID 26173815
  3. The SET domain protein, Set3p, promotes the reliable execution of cytokinesis in Schizosaccharomyces pombe. Rentas S, et al. PLoS One, 2012. PMID 22347452, Free PMC Article
  4. A conserved histone deacetylase with a role in the regulation of cytokinesis in Schizosaccharomyces pombe. Grewal C, et al. Cell Div, 2012 May 4. PMID 22559741, Free PMC Article
  5. Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Shevchenko A, et al. Genome Biol, 2008. PMID 19040720, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables methylated histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables promoter-specific chromatin binding IDA
Inferred from Direct Assay
more info
 PubMed 
contributes_to transcription corepressor activity IC
Inferred by Curator
more info
  
Process Evidence Code Pubs
involved_in negative regulation of gene expression, epigenetic IC
Inferred by Curator
more info
  
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Rpd3L-Expanded complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Rpd3L-Expanded complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of Set3 complex EXP
Inferred from Experiment
more info
 PubMed 
part_of Set3 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Set3 complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
NOT is_active_in pericentric heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
putative histone H3 lysine methyltransferase Set3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5039546..5042744 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020266.3 → NP_594837.1  putative histone H3 lysine methyltransferase Set3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594837.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10362, Q9USE1
    Conserved Domains (3) summary
    smart00317
    Location:215 → 343
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    COG2940
    Location:284 → 826
    SET; SET domain-containing protein (function unknown) [General function prediction only]
    cd15550
    Location:5 → 48
    PHD_MLL5; PHD finger found in mixed lineage leukemia 5 (MLL5)
Nucleotide Protein
Heading Accession and Version

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