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str3 siderophore-Fe(3+) transporter Str3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541891, updated on 18-Sep-2024

Summary

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Official Symbol
str3
Official Full Name
siderophore-Fe(3+) transporter Str3
Primary source
PomBase:SPAC1F8.03c
Locus tag
SPOM_SPAC1F8.03C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See str3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (88201..90289, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene plasma membrane gluconate:proton symporter Ght3 Neighboring gene ncRNA Neighboring gene protein Shu1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3. Ping FLY, et al. Mol Microbiol, 2024 Jul. PMID 38778742
  2. Hemeprotein Tpx1 interacts with cell-surface heme transporter Str3 in Schizosaccharomyces pombe. Normant V, et al. Mol Microbiol, 2021 Apr. PMID 33140466
  3. The major facilitator transporter Str3 is required for low-affinity heme acquisition in Schizosaccharomyces pombe. Normant V, et al. J Biol Chem, 2018 Apr 27. PMID 29549126, Free PMC Article
  4. Promoter nucleosome dynamics regulated by signalling through the CTD code. Materne P, et al. Elife, 2015 Jun 22. PMID 26098123, Free PMC Article
  5. Expanded Interactome of the Intrinsically Disordered Protein Dss1. Schenstrøm SM, et al. Cell Rep, 2018 Oct 23. PMID 30355493, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3.
    Title: The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3.
  2. Hemeprotein Tpx1 interacts with cell-surface heme transporter Str3 in Schizosaccharomyces pombe.
    Title: Hemeprotein Tpx1 interacts with cell-surface heme transporter Str3 in Schizosaccharomyces pombe.
  3. Further analysis by absorbance spectroscopy disclosed that a predicted extracellular loop region in Str3 containing the two putative heme-binding motifs interacts with hemin, with a KD of 6.6 mum Taken together, these results indicate that Str3 is a second cell-surface membrane protein for acquisition of exogenous heme in S. pombe.
    Title: The major facilitator transporter Str3 is required for low-affinity heme acquisition in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables heme binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables heme transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in heme import across plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
siderophore-Fe(3+) transporter Str3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    88201..90289 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018192.3 → NP_592792.1  siderophore-Fe(3+) transporter Str3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_592792.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q92341
    Conserved Domains (2) summary
    cd06174
    Location:85 → 503
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:120 → 400
    MFS_1; Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials