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cph2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541422, updated on 11-Sep-2024

Summary

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Official Symbol
cph2
Primary source
PomBase:SPAC2F7.07c
Locus tag
SPOM_SPAC2F7.07C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
rco1
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Genomic context

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Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (544127..546259, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene mediator complex subunit Med1 Neighboring gene ncRNA Neighboring gene translation initiation factor Tif5 Neighboring gene DNA polymerase X family Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SWI/SNF complex subunit Snf5 Neighboring gene GTPase-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Two fission yeast high mobility group box proteins in the maintenance of genomic integrity following doxorubicin insult. Tang MY, et al. Gene, 2015 May 10. PMID 25701403
  2. A genetic screen for functional partners of condensin in fission yeast. Robellet X, et al. G3 (Bethesda), 2014 Feb 19. PMID 24362309, Free PMC Article
  3. Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection. Nicolas E, et al. Nat Struct Mol Biol, 2007 May. PMID 17450151
  4. Two assembly modes for SIN3 histone deacetylase complexes. Wang C, et al. Cell Discov, 2023 Apr 19. PMID 37076472, Free PMC Article
  5. Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast. Nguyen TT, et al. Sci Rep, 2015 Feb 11. PMID 25669599, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables molecular adaptor activity EXP
Inferred from Experiment
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription initiation-coupled chromatin remodeling IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of Rpd3S complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Rpd3S complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic spindle HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
Clr6 histone deacetylase-associated PHD protein-2 Cph2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    544127..546259 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018378.3 → NP_592978.1  Clr6 histone deacetylase-associated PHD protein-2 Cph2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_592978.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q09698
    Conserved Domains (2) summary
    cd15534
    Location:408 → 456
    PHD2_PHF12_Rco1; PHD finger 2 found in PHD finger protein 12 (PHF12), yeast Rco1, and similar proteins
    cd15535
    Location:265 → 309
    PHD1_Rco1; PHD finger 1 found in Saccharomyces cerevisiae transcriptional regulatory protein Rco1 and similar proteins
Nucleotide Protein
Heading Accession and Version

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