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ctf18 Ctf18 RFC-like complex subunit Ctf18 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541270, updated on 18-Sep-2024

Summary

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Official Symbol
ctf18
Official Full Name
Ctf18 RFC-like complex subunit Ctf18
Primary source
PomBase:SPBC902.02c
Locus tag
SPOM_SPBC902.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
chl12
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Genomic context

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See ctf18 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (483878..486967, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene U3 snoRNP protein Utp15 Neighboring gene gamma tubulin complex GCP3 subunit Alp6 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein phosphatase regulator Nem2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Checkpoint-dependent and -independent roles of Swi3 in replication fork recovery and sister chromatid cohesion in fission yeast. Rapp JB, et al. PLoS One, 2010 Oct 12. PMID 20967229, Free PMC Article
  2. Kinetochore geometry defined by cohesion within the centromere. Sakuno T, et al. Nature, 2009 Apr 16. PMID 19370027
  3. Roles of the checkpoint sensor clamp Rad9-Rad1-Hus1 (911)-complex and the clamp loaders Rad17-RFC and Ctf18-RFC in Schizosaccharomyces pombe telomere maintenance. Khair L, et al. Cell Cycle, 2010 Jun 1. PMID 20505337, Free PMC Article
  4. Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast. Kim J, et al. Nucleic Acids Res, 2005. PMID 16040599, Free PMC Article
  5. New functions of Ctf18-RFC in preserving genome stability outside its role in sister chromatid cohesion. Gellon L, et al. PLoS Genet, 2011 Feb 10. PMID 21347277, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Together these results indicate that Ctf18-RFC has additional important functions in preserving genome stability, besides its role in sister chromatid cohesion, which we propose include lesion bypass by replication forks and post-replication repair.
    Title: New functions of Ctf18-RFC in preserving genome stability outside its role in sister chromatid cohesion.
  2. RFC(Ctf18) and the Swi1-Swi3 complex function in separate and redundant pathways essential for replication fork stabilization to facilitate sister chromatid cohesion in fission yeast.
    Title: RFCCtf18 and the Swi1-Swi3 complex function in separate and redundant pathways required for the stabilization of replication forks to facilitate sister chromatid cohesion in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity NAS
Non-traceable Author Statement
more info
  
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to DNA clamp loader activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in DNA-templated DNA replication maintenance of fidelity IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in DNA-templated DNA replication maintenance of fidelity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of Ctf18 RFC-like complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nuclear replication fork IC
Inferred by Curator
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Ctf18 RFC-like complex subunit Ctf18

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    483878..486967 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021106.3 → NP_595200.1  Ctf18 RFC-like complex subunit Ctf18 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595200.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9USQ1, Q9UTY7
    Conserved Domains (3) summary
    cd00009
    Location:412 → 553
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00382
    Location:416 → 554
    AAA; ATPases associated with a variety of cellular activities
    COG0470
    Location:482 → 647
    HolB; DNA polymerase III, delta prime subunit [Replication, recombination and repair]
Nucleotide Protein
Heading Accession and Version

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