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fic1 contractile ring-membrane anchor Fic1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541203, updated on 18-Sep-2024

Summary

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Official Symbol
fic1
Official Full Name
contractile ring-membrane anchor Fic1
Primary source
PomBase:SPBC83.18c
Locus tag
SPOM_SPBC83.18C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See fic1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003423.3 (1543492..1544775, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene multiprotein bridging factor Mbf1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Atf-CREB family transcription factor Atf1 Neighboring gene ncRNA Neighboring gene plasma membrane OPT oligopeptide transmembrane transporter family Isp4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The fission yeast cytokinetic ring component Fic1 promotes septum formation. Rossi AM, et al. Biol Open, 2023 May 15. PMID 37158439, Free PMC Article
  2. Phosphoregulation of the cytokinetic protein Fic1 contributes to fission yeast growth polarity establishment. Bohnert KA, et al. J Cell Sci, 2020 Sep 17. PMID 32878942, Free PMC Article
  3. DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division. Bhattacharjee R, et al. Mol Biol Cell, 2020 Apr 15. PMID 32101481, Free PMC Article
  4. F-BAR domain protein Rga7 collaborates with Cdc15 and Imp2 to ensure proper cytokinesis in fission yeast. Martín-García R, et al. J Cell Sci, 2014 Oct 1. PMID 25052092
  5. Multiple polarity kinases inhibit phase separation of F-BAR protein Cdc15 and antagonize cytokinetic ring assembly in fission yeast. Bhattacharjee R, et al. Elife, 2023 Feb 7. PMID 36749320, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables cytoskeletal protein-membrane anchor activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables phospholipid binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in actin cortical patch localization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in establishment or maintenance of bipolar cell polarity IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in mitotic actomyosin contractile ring assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitotic actomyosin contractile ring contraction EXP
Inferred from Experiment
more info
 PubMed 
involved_in mitotic cytokinesis EXP
Inferred from Experiment
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cell cortex of cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell division site HDA PubMed 
is_active_in cell division site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell tip HDA PubMed 
is_active_in cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic actomyosin contractile ring IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic actomyosin contractile ring, intermediate layer IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
contractile ring-membrane anchor Fic1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1543492..1544775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021545.3 → NP_595651.1  contractile ring-membrane anchor Fic1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595651.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94701
    Conserved Domains (1) summary
    cd08681
    Location:7 → 125
    C2_fungal_Inn1p-like; C2 domain found in fungal Ingression 1 (Inn1) proteins
Nucleotide Protein
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