U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

stn1 telomere cap complex subunit Stn1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541052, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
stn1
Official Full Name
telomere cap complex subunit Stn1
Primary source
PomBase:SPBC409.12c
Locus tag
SPOM_SPBC409.12C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See stn1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (1161485..1163082, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein meu18 Neighboring gene tRNA-Arg Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein mim2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Fission yeast Stn1 maintains stability of repetitive DNA at subtelomere and ribosomal DNA regions. Yamamoto I, et al. Nucleic Acids Res, 2021 Oct 11. PMID 34520548, Free PMC Article
  2. The fission yeast Stn1-Ten1 complex limits telomerase activity via its SUMO-interacting motif and promotes telomeres replication. Matmati S, et al. Sci Adv, 2018 May. PMID 29774234, Free PMC Article
  3. Ssu72 phosphatase is a conserved telomere replication terminator. Escandell JM, et al. EMBO J, 2019 Apr 1. PMID 30796050, Free PMC Article
  4. Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres. Sun J, et al. Genes Dev, 2009 Dec 15. PMID 20008938, Free PMC Article
  5. Protection of telomeres by a conserved Stn1-Ten1 complex. Martín V, et al. Proc Natl Acad Sci U S A, 2007 Aug 28. PMID 17715303, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Fission yeast Stn1 maintains stability of repetitive DNA at subtelomere and ribosomal DNA regions.
    Title: Fission yeast Stn1 maintains stability of repetitive DNA at subtelomere and ribosomal DNA regions.
  2. Isolated a high-temperature sensitive stn1 allele (termed stn1-1). stn1-1 cells abruptly lost telomeric sequence almost completely at the restrictive temperature. The loss of chromosomal DNA happened without gradual telomere shortening, and extended to 30 kb from the ends of chromosomes.
    Title: Fission yeast Stn1 is crucial for semi-conservative replication at telomeres and subtelomeres.
  3. SUMO inhibits telomerase through stimulation of Stn1/Ten1 action by Tpz1.
    Title: Tpz1TPP1 SUMOylation reveals evolutionary conservation of SUMO-dependent Stn1 telomere association.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables single-stranded telomeric DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables telomeric DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in telomere capping IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in telomere maintenance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of CST complex EXP
Inferred from Experiment
more info
 PubMed 
part_of CST complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in chromosome, telomeric region IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in chromosome, telomeric repeat region IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
part_of telomere cap complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
telomere cap complex subunit Stn1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1161485..1163082 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001356152.2 → NP_001343021.1  telomere cap complex subunit Stn1 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q0E7J7
    Conserved Domains (1) summary
    pfam10451
    Location:1 → 216
    Stn1; Telomere regulation protein Stn1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.