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sec63 translocation subcomplex subunit Sec63 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540961, updated on 18-Sep-2024

Summary

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Official Symbol
sec63
Official Full Name
translocation subcomplex subunit Sec63
Primary source
PomBase:SPBC36B7.03
Locus tag
SPOM_SPBC36B7.03
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See sec63 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (2387072..2389366)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene translocon subunit Sec61-like protein Neighboring gene ncRNA Neighboring gene ER to Golgi ceramide transport protein, lipocalin superfamily Svf2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA dihydrouridine synthase Dus1 Neighboring gene ncRNA Neighboring gene ubiquitin-protein ligase E/phosphatidylinositol(3)-phosphate binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The actomyosin ring recruits early secretory compartments to the division site in fission yeast. Vjestica A, et al. Mol Biol Cell, 2008 Mar. PMID 18184749, Free PMC Article
  2. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
  3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
  4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
  5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables Hsp70 protein binding ISM
Inferred from Sequence Model
more info
  
enables protein transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in SRP-dependent cotranslational protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in post-translational protein targeting to endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Sec62/Sec63 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cortical endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in endoplasmic reticulum HDA PubMed 
is_active_in nuclear outer membrane-endoplasmic reticulum membrane network IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
translocation subcomplex subunit Sec63

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2387072..2389366
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021892.3 → NP_595985.1  translocation subcomplex subunit Sec63 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595985.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9HGN7
    Conserved Domains (4) summary
    smart00973
    Location:229 → 541
    Sec63; Sec63 Brl domain
    COG5407
    Location:1 → 611
    SEC63; Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport]
    pfam00226
    Location:98 → 164
    DnaJ; DnaJ domain
    pfam12753
    Location:543 → 599
    Nro1; Nuclear pore complex subunit Nro1
Nucleotide Protein
Heading Accession and Version

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