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pmt3 small ubiquitin-like modifier pmt3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540927, updated on 18-Sep-2024

Summary

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Official Symbol
pmt3
Official Full Name
small ubiquitin-like modifier pmt3
Primary source
PomBase:SPBC365.06
Locus tag
SPOM_SPBC365.06
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
smt3; ubl2
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Genomic context

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See pmt3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003423.3 (2506845..2510260)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene RNA-binding and ribosome biogenesis protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene splicing factor Slu7 Neighboring gene TATA element modulatory factor-like protein Neighboring gene Der1 family protein Neighboring gene KIN17-like protein Neighboring gene Ino80 complex actin-like protein Arp5 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of a fission yeast SUMO-1 homologue, pmt3p, required for multiple nuclear events, including the control of telomere length and chromosome segregation. Tanaka K, et al. Mol Cell Biol, 1999 Dec. PMID 10567589, Free PMC Article
  2. The telomere-binding protein Taz1p as a target for modification by a SUMO-1 homologue in fission yeast. Spink K, et al. Biochem Genet, 2005 Apr. PMID 15932060
  3. The fission yeast Stn1-Ten1 complex limits telomerase activity via its SUMO-interacting motif and promotes telomeres replication. Matmati S, et al. Sci Adv, 2018 May. PMID 29774234, Free PMC Article
  4. Targeting of SUMO substrates to a Cdc48-Ufd1-Npl4 segregase and STUbL pathway in fission yeast. Køhler JB, et al. Nat Commun, 2015 Nov 5. PMID 26537787, Free PMC Article
  5. Characterization of SUMO-conjugating enzyme mutants in Schizosaccharomyces pombe identifies a dominant-negative allele that severely reduces SUMO conjugation. Ho JC, et al. Biochem J, 2003 May 15. PMID 12597774, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that pmt3 mutants exhibiting hypersensitivity to cisplatin.
    Title: Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast.
  2. interaction between Taz1 and Pmt3p
    Title: The telomere-binding protein Taz1p as a target for modification by a SUMO-1 homologue in fission yeast.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein tag activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein tag activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ubiquitin-like protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in mitotic recombination-dependent replication fork processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein sumoylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in stalled replication fork localization to nuclear periphery IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in telomere maintenance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in linear element IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic spindle pole body HDA PubMed 
is_active_in mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in septin ring IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
small ubiquitin-like modifier pmt3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2506845..2510260
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001355775.2 → NP_001342889.1  small ubiquitin-like modifier pmt3 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13351, O74186
    Conserved Domains (1) summary
    COG5227
    Location:1 → 114
    SMT3; Ubiquitin-like protein (sentrin) [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein
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