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swd2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540788, updated on 11-Sep-2024

Summary

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Official Symbol
swd2
Primary source
PomBase:SPBC18H10.06c
Locus tag
SPOM_SPBC18H10.06C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
swd2.1
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Genomic context

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Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (1781945..1783219, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene WD repeat-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene WW domain-binding protein 4 Neighboring gene ubiquitin hydrolase Ubp4 Neighboring gene zf-CHY type zinc finger protein Neighboring gene splicing-associated factor Saf4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Histone H2B ubiquitylation promotes activity of the intact Set1 histone methyltransferase complex in fission yeast. Racine A, et al. J Biol Chem, 2012 Jun 1. PMID 22505722, Free PMC Article
  2. High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts. Roguev A, et al. J Biol Chem, 2003 Mar 7. PMID 12488447
  3. The fission yeast spSet1p is a histone H3-K4 methyltransferase that functions in telomere maintenance and DNA repair in an ATM kinase Rad3-dependent pathway. Kanoh J, et al. J Mol Biol, 2003 Feb 28. PMID 12589755
  4. A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Roguev A, et al. Mol Cell Proteomics, 2004 Feb. PMID 14617822
  5. Abo1 is required for the H3K9me2 to H3K9me3 transition in heterochromatin. Dong W, et al. Sci Rep, 2020 Apr 8. PMID 32269268, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in transcription initiation-coupled chromatin remodeling IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of Set1C/COMPASS complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Set1C/COMPASS complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of chromatin IC
Inferred by Curator
more info
 PubMed 
is_active_in cytosol HDA PubMed 

General protein information

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Preferred Names
Set1C complex subunit Swd2.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1781945..1783219 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021628.3 → NP_595730.1  Set1C complex subunit Swd2.1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595730.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O60137
    Conserved Domains (3) summary
    COG2319
    Location:3 → 281
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:29 → 66
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:27 → 281
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version

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