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rsc1 RSC complex bromodomain subunit Rsc1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540749, updated on 18-Sep-2024

Summary

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Official Symbol
rsc1
Official Full Name
RSC complex bromodomain subunit Rsc1
Primary source
PomBase:SPBC4B4.03
Locus tag
SPOM_SPBC4B4.03
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See rsc1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (3416002..3418693)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Fbl-like pantothenate kinase Neighboring gene protein Nca2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene translation initiation factor eIF2A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Combinatorial, site-specific requirement for heterochromatic silencing factors in the elimination of nucleosome-free regions. Garcia JF, et al. Genes Dev, 2010 Aug 15. PMID 20675407, Free PMC Article
  2. Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast. Monahan BJ, et al. Nat Struct Mol Biol, 2008 Aug. PMID 18622392, Free PMC Article
  3. Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B. Buttrick GJ, et al. Mol Biol Cell, 2011 Dec. PMID 21965289, Free PMC Article
  4. Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast. Nguyen TT, et al. Sci Rep, 2015 Feb 11. PMID 25669599, Free PMC Article
  5. Promoter nucleosome dynamics regulated by signalling through the CTD code. Materne P, et al. Elife, 2015 Jun 22. PMID 26098123, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription elongation by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription initiation-coupled chromatin remodeling IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of RSC-type complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RSC-type complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
RSC complex bromodomain subunit Rsc1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3416002..3418693
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022339.3 → NP_596420.1  RSC complex bromodomain subunit Rsc1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596420.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74964
    Conserved Domains (5) summary
    cd05522
    Location:211 → 312
    Bromo_Rsc1_2_II; Bromodomain, repeat II in Rsc1/2_like subfamily, specific to fungi. Rsc1 and Rsc2 are components of the RSC complex (remodeling the structure of chromatin), are essential for transcriptional control, and have a specific domain architecture including two ...
    smart00297
    Location:11 → 117
    BROMO; bromo domain
    COG5076
    Location:66 → 447
    COG5076; Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
    cd04717
    Location:350 → 470
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...
    cl00447
    Location:688 → 782
    Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
Nucleotide Protein
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