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med14 mediator complex subunit Med14 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540678, updated on 18-Sep-2024

Summary

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Official Symbol
med14
Official Full Name
mediator complex subunit Med14
Primary source
PomBase:SPBC1A4.10c
Locus tag
SPOM_SPBC1A4.10C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
pmc1; SPBP23A10.01c
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Genomic context

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See med14 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (1996006..1999093, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudouridine synthase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ACN9 family protein Neighboring gene V-ATPase assembly factor Pkr1 Neighboring gene anaphase-promoting complex cullin family subunit Apc2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of a fission yeast P(5)-type ATPase homologue that is essential for Ca(2+)/Mn(2+ )homeostasis in the absence of P(2)-type ATPases. Furune T, et al. Genes Genet Syst, 2008 Oct. PMID 19168988
  2. A chromatin-remodeling protein is a component of fission yeast mediator. Khorosjutina O, et al. J Biol Chem, 2010 Sep 24. PMID 20622008, Free PMC Article
  3. Fission yeast TOR signaling is essential for the down-regulation of a hyperactivated stress-response MAP kinase under salt stress. Ishiguro J, et al. Mol Genet Genomics, 2013 Feb. PMID 23271606
  4. Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells. Spåhr H, et al. Proc Natl Acad Sci U S A, 2001 Oct 9. PMID 11572939, Free PMC Article
  5. Mediator is required for activated transcription in a Schizosaccharomyces pombe in vitro system. Tamayo E, et al. Eur J Biochem, 2004 Jun. PMID 15182371

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables transcription coactivator activity EXP
Inferred from Experiment
more info
 PubMed 
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription initiation by RNA polymerase II EXP
Inferred from Experiment
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription initiation at RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of core mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mediator complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
mediator complex subunit Med14

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1996006..1999093 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021716.4 → NP_595813.2  mediator complex subunit Med14 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595813.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74344, Q9P7Y4
    Conserved Domains (1) summary
    pfam08638
    Location:13 → 203
    Med14; Mediator complex subunit MED14
Nucleotide Protein
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