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mlo3 RNA-binding protein Mlo3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540565, updated on 18-Sep-2024

Summary

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Official Symbol
mlo3
Official Full Name
RNA-binding protein Mlo3
Primary source
PomBase:SPBC1D7.04
Locus tag
SPOM_SPBC1D7.04
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPBC1D7.04c
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Genomic context

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See mlo3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (1743968..1744748, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene MAP kinase kinase kinase Byr2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cyclin Clg1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Conserved RNA Binding Cyclophilin, Rct1, Regulates Small RNA Biogenesis and Splicing Independent of Heterochromatin Assembly. Chang AY, et al. Cell Rep, 2017 Jun 20. PMID 28636937, Free PMC Article
  2. Homolog of BRCA2-interacting Dss1p and Uap56p link Mlo3p and Rae1p for mRNA export in fission yeast. Thakurta AG, et al. EMBO J, 2005 Jul 20. PMID 15990877, Free PMC Article
  3. Clr4 specificity and catalytic activity beyond H3K9 methylation. Kusevic D, et al. Biochimie, 2017 Apr. PMID 28143796
  4. Defects in RNA quality control factors reveal RNAi-independent nucleation of heterochromatin. Reyes-Turcu FE, et al. Nat Struct Mol Biol, 2011 Sep 4. PMID 21892171, Free PMC Article
  5. Characterization of the ptr5+ gene involved in nuclear mRNA export in fission yeast. Watanabe N, et al. Biochem Biophys Res Commun, 2012 Feb 3. PMID 22240020

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. First demonstration of a direct role for mlo3 in mRNA export in S. pombe
    Title: Homolog of BRCA2-interacting Dss1p and Uap56p link Mlo3p and Rae1p for mRNA export in fission yeast.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear polyadenylation-dependent antisense transcript catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in siRNA catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in chromosome, centromeric region IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in euchromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of transcription export complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
RNA-binding protein Mlo3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1743968..1744748 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021613.3 → NP_595715.1  RNA-binding protein Mlo3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595715.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q09330
    Conserved Domains (2) summary
    COG0724
    Location:2 → 196
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12267
    Location:56 → 132
    RRM_YRA1_MLO3; RNA recognition motif in yeast RNA annealing protein YRA1 (Yra1p), yeast mRNA export protein mlo3 and similar proteins
Nucleotide Protein
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