U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

efc25 Ras guanine nucleotide exchange factor efc25 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540248, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
efc25
Official Full Name
Ras guanine nucleotide exchange factor efc25
Primary source
PomBase:SPBC336.03
Locus tag
SPOM_SPBC336.03
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See efc25 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2739672..2743519)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SSU rRNA dimethylase Neighboring gene ncRNA Neighboring gene DNA polymerase delta catalytic subunit Cdc6 Neighboring gene S-adenosylmethionine-dependent methyltransferase Neighboring gene ncRNA Neighboring gene ribonuclease H Rnh1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Cloning and characterization of the S. pombe gene efc25+, a new putative guanine nucleotide exchange factor. Tratner I, et al. Gene, 1997 Jul 9. PMID 9256078
  2. Two ras pathways in fission yeast are differentially regulated by two ras guanine nucleotide exchange factors. Papadaki P, et al. Mol Cell Biol, 2002 Jul. PMID 12052869, Free PMC Article
  3. Spatial control of translation repression and polarized growth by conserved NDR kinase Orb6 and RNA-binding protein Sts5. Nuñez I, et al. Elife, 2016 Jul 30. PMID 27474797, Free PMC Article
  4. The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components. Salas-Pino S, et al. J Cell Biol, 2017 Nov 6. PMID 28974540, Free PMC Article
  5. Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast. Navarro FJ, et al. J Cell Sci, 2017 Dec 15. PMID 29084823, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables guanyl-nucleotide exchange factor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in establishment or maintenance of cell polarity IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in establishment or maintenance of cell polarity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in signaling NAS
Non-traceable Author Statement
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Ras guanine nucleotide exchange factor efc25

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2739672..2743519
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022041.3 → NP_596123.1  Ras guanine nucleotide exchange factor efc25 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596123.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9USU1
    Conserved Domains (2) summary
    pfam00617
    Location:755 → 932
    RasGEF; RasGEF domain
    pfam00618
    Location:593 → 700
    RasGEF_N; RasGEF N-terminal motif
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous