gtb1 gamma-tubulin Gtb1 [Schizosaccharomyces pombe (fission yeast)] - Gene

Summary

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Official Symbol: gtb1
Official Full Name: gamma-tubulin Gtb1
Primary source: PomBase:SPBC32F12.04
Locus tag: SPOM_SPBC32F12.04
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Schizosaccharomyces pombe (strain: 972h-)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as: tug1
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Genomic context

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See gtb1 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 7

Sequence:: Chromosome: II; NC_003423.3 (2791351..2794184)

Chromosome II - NC_003423.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Microtubule stabilization by the gamma-tubulin complexis is important for maintaining the organization and dynamic behavior of microtubule.
Title: Microtubule stabilization in vivo by nucleation-incompetent γ-tubulin complex.
pericentrin-like Pcp1 regulates multiple functions of the spindle pole body (SPB) through recruiting two critical factors, the gamma-tubulin complex (gamma-TuC) and polo kinase (Plo1)
Title: Fission yeast Pcp1 links polo kinase-mediated mitotic entry to gamma-tubulin-dependent spindle formation.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by PomBase

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables microtubule nucleator activity	EXP Inferred from Experiment more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables structural constituent of cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cytoplasmic microtubule organization	IC Inferred by Curator more info
involved_in meiotic spindle organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in microtubule nucleation	IBA Inferred from Biological aspect of Ancestor more info
involved_in microtubule nucleation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitotic cytokinesis, division site positioning	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitotic sister chromatid segregation	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitotic spindle midzone assembly	IGI Inferred from Genetic Interaction more info	PubMed
involved_in mitotic spindle organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitotic spindle organization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in equatorial microtubule organizing center	IDA Inferred from Direct Assay more info	PubMed
part_of gamma-tubulin complex	IBA Inferred from Biological aspect of Ancestor more info
part_of gamma-tubulin ring complex	IDA Inferred from Direct Assay more info	PubMed
part_of gamma-tubulin small complex	IDA Inferred from Direct Assay more info	PubMed
is_active_in half bridge of mitotic spindle pole body	IDA Inferred from Direct Assay more info	PubMed
is_active_in inner plaque of mitotic spindle pole body	IDA Inferred from Direct Assay more info	PubMed
is_active_in interphase microtubule organizing center	IDA Inferred from Direct Assay more info	PubMed
is_active_in mating projection tip	IDA Inferred from Direct Assay more info	PubMed
is_active_in microtubule	IBA Inferred from Biological aspect of Ancestor more info
is_active_in microtubule	IEA Inferred from Electronic Annotation more info
is_active_in mitotic spindle pole body	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IDA Inferred from Direct Assay more info	PubMed
is_active_in old mitotic spindle pole body	IDA Inferred from Direct Assay more info	PubMed
is_active_in outer plaque of mitotic spindle pole body	IDA Inferred from Direct Assay more info	PubMed
is_active_in spindle	IBA Inferred from Biological aspect of Ancestor more info
is_active_in spindle pole body	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: gamma-tubulin Gtb1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003423.3 Reference assembly

Range

2791351..2794184

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001022066.3 → NP_596147.1 gamma-tubulin Gtb1 [Schizosaccharomyces pombe]

See identical proteins and their annotated locations for NP_596147.1

Status: PROVISIONAL

UniProtKB/Swiss-Prot

P25295

Conserved Domains (2) summary

PLN00222
Location:1 → 444

PLN00222; tubulin gamma chain; Provisional

cd02188
Location:3 → 435

gamma_tubulin; The gamma-tubulin family