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git5 heterotrimeric G protein beta (WD repeat) subunit Git5 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539974, updated on 18-Sep-2024

Summary

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Official Symbol
git5
Official Full Name
heterotrimeric G protein beta (WD repeat) subunit Git5
Primary source
PomBase:SPBC32H8.07
Locus tag
SPOM_SPBC32H8.07
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
gpb1
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Genomic context

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See git5 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (1463849..1465745)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein Llp1 Neighboring gene TPR repeat-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene putative alpha-1,2-mannosyltransferase Omh5 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The G protein beta subunit Gpb1 of Schizosaccharomyces pombe is a negative regulator of sexual development. Kim DU, et al. Mol Gen Genet, 1996 Aug 27. PMID 8804400
  2. The fission yeast git5 gene encodes a Gbeta subunit required for glucose-triggered adenylate cyclase activation. Landry S, et al. Genetics, 2000 Apr. PMID 10747045, Free PMC Article
  3. Glucose monitoring in fission yeast via the Gpa2 galpha, the git5 Gbeta and the git3 putative glucose receptor. Welton RM, et al. Genetics, 2000 Oct. PMID 11014802, Free PMC Article
  4. Glucose repression of fbp1 transcription of Schizosaccharomyces pombe is partially regulated by adenylate cyclase activation by a G protein alpha subunit encoded by gpa2 (git8). Nocero M, et al. Genetics, 1994 Sep. PMID 8001792, Free PMC Article
  5. Activated alleles of the Schizosaccharomyces pombe gpa2+ Galpha gene identify residues involved in GDP-GTP exchange. Ivey FD, et al. Eukaryot Cell, 2010 Apr. PMID 20139237, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables signaling receptor complex adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables signaling receptor complex adaptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of induction of conjugation with cellular fusion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
part_of heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of heterotrimeric G-protein complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
heterotrimeric G protein beta (WD repeat) subunit Git5

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1463849..1465745
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021508.3 → NP_595613.1  heterotrimeric G protein beta (WD repeat) subunit Git5 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595613.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10282
    Conserved Domains (3) summary
    COG2319
    Location:1 → 302
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:14 → 302
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:66 → 104
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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