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csc3 WD repeat-containing protein [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539970, updated on 18-Sep-2024

Summary

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Official Symbol
csc3
Official Full Name
WD repeat-containing protein
Primary source
PomBase:SPBC1773.01
Locus tag
SPOM_SPBC1773.01
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
far8
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Genomic context

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See csc3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (281551..283779)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ubiquitin family protein Neighboring gene ncRNA Neighboring gene centromere receptor protein cnp20 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene thioredoxin peroxidase Neighboring gene tRNA-Gly

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transient PP2A SIP complex localization to mitotic SPBs for SIN inhibition is mediated solely by the Csc1 FHA domain. Willet AH, et al. Mol Biol Cell, 2024 Aug 1. PMID 38865179, Free PMC Article
  2. Cdk1 promotes cytokinesis in fission yeast through activation of the septation initiation network. Rachfall N, et al. Mol Biol Cell, 2014 Aug 1. PMID 24920823, Free PMC Article
  3. Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions. Frost A, et al. Cell, 2012 Jun 8. PMID 22682253, Free PMC Article
  4. SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast. Singh NS, et al. Curr Biol, 2011 Dec 6. PMID 22119525, Free PMC Article
  5. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in asymmetric protein localization to old mitotic spindle pole body IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of septation initiation signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of septation initiation signaling IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in regulation of signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of FAR/SIN/STRIPAK complex EXP
Inferred from Experiment
more info
 PubMed 
part_of FAR/SIN/STRIPAK complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of FAR/SIN/STRIPAK complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm HDA PubMed 
is_active_in mitotic spindle pole body EXP
Inferred from Experiment
more info
 PubMed 
is_active_in nuclear envelope IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in old mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
WD repeat-containing protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    281551..283779
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021023.3 → NP_595116.1  WD repeat-containing protein [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595116.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94560
    Conserved Domains (4) summary
    COG2319
    Location:303 → 532
    WD40; WD40 repeat [General function prediction only]
    pfam08232
    Location:23 → 138
    Striatin; Striatin family
    sd00039
    Location:342 → 388
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:303 → 565
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
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