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ste20 target of rapamycin complex 2 subunit ste20 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539845, updated on 18-Sep-2024

Summary

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Official Symbol
ste20
Official Full Name
target of rapamycin complex 2 subunit ste20
Primary source
PomBase:SPBC12C2.02c
Locus tag
SPOM_SPBC12C2.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
ste16
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Genomic context

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See ste20 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2475879..2480462)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene methionine synthase reductase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene PAK-like kinase Nak1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Modulation of TOR complex 2 signaling by the stress-activated MAPK pathway in fission yeast. Morigasaki S, et al. J Cell Sci, 2019 Oct 10. PMID 31477575
  2. Fission yeast Ryh1 GTPase activates TOR Complex 2 in response to glucose. Hatano T, et al. Cell Cycle, 2015. PMID 25590601, Free PMC Article
  3. Fission yeast TOR complex 2 activates the AGC-family Gad8 kinase essential for stress resistance and cell cycle control. Ikeda K, et al. Cell Cycle, 2008 Feb 1. PMID 18235227, Free PMC Article
  4. Loss of the TOR kinase Tor2 mimics nitrogen starvation and activates the sexual development pathway in fission yeast. Matsuo T, et al. Mol Cell Biol, 2007 Apr. PMID 17261596, Free PMC Article
  5. Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit. Tatebe H, et al. Elife, 2017 Mar 7. PMID 28264193, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in TORC2 signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in TORC2 signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of TORC2 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of TORC2 complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell cortex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell division site HDA PubMed 
is_active_in cytoplasm HDA PubMed 
is_active_in cytosol HDA PubMed 
is_active_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
target of rapamycin complex 2 subunit ste20

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2475879..2480462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021929.3 → NP_596021.1  target of rapamycin complex 2 subunit ste20 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596021.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q09743
    Conserved Domains (5) summary
    pfam14663
    Location:926 → 1025
    RasGEF_N_2; Rapamycin-insensitive companion of mTOR RasGEF_N domain
    pfam14664
    Location:237 → 612
    RICTOR_N; Rapamycin-insensitive companion of mTOR, N-term
    pfam14666
    Location:697 → 917
    RICTOR_M; Rapamycin-insensitive companion of mTOR, middle domain
    pfam14668
    Location:1095 → 1163
    RICTOR_V; Rapamycin-insensitive companion of mTOR, domain 5
    cl00087
    Location:34 → 108
    HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
Nucleotide Protein
Heading Accession and Version

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