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cut3 condensin complex SMC subunit Smc4 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539817, updated on 18-Sep-2024

Summary

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Official Symbol
cut3
Official Full Name
condensin complex SMC subunit Smc4
Primary source
PomBase:SPBC146.03c
Locus tag
SPOM_SPBC146.03C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
smc4
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Genomic context

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See cut3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (1002263..1006523, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene mediator complex subunit Med15 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene sulfhydryl oxidase Neighboring gene protein Cwf25

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cti1/C1D interacts with condensin SMC hinge and supports the DNA repair function of condensin. Chen ES, et al. Proc Natl Acad Sci U S A, 2004 May 25. PMID 15148393, Free PMC Article
  2. DNA renaturation activity of the SMC complex implicated in chromosome condensation. Sutani T, et al. Nature, 1997 Aug 21. PMID 9285594
  3. Condensin Promotes Position Effects within Tandem DNA Repeats via the RITS Complex. He H, et al. Cell Rep, 2016 Feb 9. PMID 26832414, Free PMC Article
  4. Involvement of condensin-directed gene associations in the organization and regulation of chromosome territories during the cell cycle. Iwasaki O, et al. Nucleic Acids Res, 2016 May 5. PMID 26704981, Free PMC Article
  5. Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis. Saka Y, et al. EMBO J, 1994 Oct 17. PMID 7957061, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. data suggest that Ccq1p and condensins Cut3p and Cut14p collaborate to mediate resolution of telomeres in mitosis and regulate intertelomeric clustering during interphase
    Title: Ccq1p and the condensin proteins Cut3p and Cut14p prevent telomere entanglements in the fission yeast Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
contributes_to ATP hydrolysis activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA translocase activity TAS
Traceable Author Statement
more info
 PubMed 
contributes_to DNA-DNA tethering activity EXP
Inferred from Experiment
more info
 PubMed 
contributes_to DNA/DNA annealing activity IDA
Inferred from Direct Assay
more info
 PubMed 
contributes_to double-stranded DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
contributes_to single-stranded DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
contributes_to topological DNA co-entrapment activity EXP
Inferred from Experiment
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitotic chromosome condensation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic chromosome condensation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in mitotic chromosome condensation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
part_of condensin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of condensin complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
condensin complex SMC subunit Smc4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1002263..1006523 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021299.3 → NP_595392.1  condensin complex SMC subunit Smc4 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595392.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P41004, Q9UTW4, Q9UUF8
    Conserved Domains (3) summary
    cd03274
    Location:1218 → 1314
    ABC_SMC4_euk; ATP-binding cassette domain of eukaryotic SMC4 proteins
    smart00968
    Location:651 → 763
    SMC_hinge; SMC proteins Flexible Hinge Domain
    COG1196
    Location:128 → 1322
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
Nucleotide Protein
Heading Accession and Version

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