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srb11 cyclin CycC-like Srb mediator subunit Srb11 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539651, updated on 18-Sep-2024

Summary

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Official Symbol
srb11
Official Full Name
cyclin CycC-like Srb mediator subunit Srb11
Primary source
PomBase:SPBC12D12.06
Locus tag
SPOM_SPBC12D12.06
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See srb11 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003423.3 (2316055..2317654)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene calcium-binding subfamily carrier protein Neighboring gene DNA polymerase zeta Rev7 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene thioredoxin Trx2 Neighboring gene tRNA-Pro

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure of the mediator subunit cyclin C and its implications for CDK8 function. Hoeppner S, et al. J Mol Biol, 2005 Jul 29. PMID 15979093
  2. Cyclin C influences the timing of mitosis in fission yeast. Banyai G, et al. Mol Biol Cell, 2017 Jul 1. PMID 28515143, Free PMC Article
  3. TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution. Samuelsen CO, et al. Proc Natl Acad Sci U S A, 2003 May 27. PMID 12738880, Free PMC Article
  4. Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe. Spåhr H, et al. J Biol Chem, 2000 Jan 14. PMID 10625684
  5. Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth. Rallis C, et al. Biol Open, 2014 Feb 15. PMID 24463365, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription coactivator activity IC
Inferred by Curator
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mediator complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cyclin CycC-like Srb mediator subunit Srb11

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2316055..2317654
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021862.3 → NP_595953.1  cyclin CycC-like Srb mediator subunit Srb11 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595953.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94503
    Conserved Domains (3) summary
    COG5333
    Location:1 → 228
    CCL1; Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, cyclin H subunit [Cell division and chromosome partitioning / Transcription / DNA replication, recombination, and repair]
    cd00043
    Location:32 → 125
    CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
    cl00050
    Location:137 → 189
    CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
Nucleotide Protein
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