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cuf2 Cu metalloregulatory transcription factor Cuf2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539483, updated on 18-Sep-2024

Summary

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Official Symbol
cuf2
Official Full Name
Cu metalloregulatory transcription factor Cuf2
Primary source
PomBase:SPCC584.02
Locus tag
SPOM_SPCC584.02
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See cuf2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003421.2 (1532126..1532753)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene sulfite reductase NADPH flavoprotein subunit Neighboring gene ncRNA Neighboring gene GTPase regulator Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cuf2 Is a Transcriptional Co-Regulator that Interacts with Mei4 for Timely Expression of Middle-Phase Meiotic Genes. Ioannoni R, et al. PLoS One, 2016. PMID 26986212, Free PMC Article
  2. Cuf2 is a novel meiosis-specific regulatory factor of meiosis maturation. Ioannoni R, et al. PLoS One, 2012. PMID 22558440, Free PMC Article
  3. Cuf2 boosts the transcription of APC/C activator Fzr1 to terminate the meiotic division cycle. Aoi Y, et al. EMBO Rep, 2013 Jun. PMID 23628763, Free PMC Article
  4. Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth. Rallis C, et al. Biol Open, 2014 Feb 15. PMID 24463365, Free PMC Article
  5. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cuf2 functions in the timely repression of the middle-phase genes during meiotic differentiation
    Title: Cuf2 is a novel meiosis-specific regulatory factor of meiosis maturation.
  2. acts as a transcriptional co-regulator that interacts with Mei4 for timely expression of middle-phase meiotic genes
    Title: Cuf2 Is a Transcriptional Co-Regulator that Interacts with Mei4 for Timely Expression of Middle-Phase Meiotic Genes.
  3. Cuf2 ensures termination of the M-phase cycle by boosting Fzr1 expression to generate functional gametes.
    Title: Cuf2 boosts the transcription of APC/C activator Fzr1 to terminate the meiotic division cycle.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific EXP
Inferred from Experiment
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables copper ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
Cu metalloregulatory transcription factor Cuf2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1532126..1532753
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023213.1 → NP_588223.1  Cu metalloregulatory transcription factor Cuf2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588223.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94588
    Conserved Domains (1) summary
    smart00412
    Location:2 → 40
    Cu_FIST; Copper-Fist
Nucleotide Protein
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