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rhp26 SNF2 family helicase Rhp26 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539473, updated on 18-Sep-2024

Summary

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Official Symbol
rhp26
Official Full Name
SNF2 family helicase Rhp26
Primary source
PomBase:SPCP25A2.02c
Locus tag
SPOM_SPCP25A2.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See rhp26 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (1178932..1182638, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene transport protein Got1 Neighboring gene ncRNA Neighboring gene thiosulfate sulfurtransferase Tum1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene THO complex subunit Tho1 Neighboring gene respiratory chain complex assembly protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular basis of chromatin remodeling by Rhp26, a yeast CSB ortholog. Wang W, et al. Proc Natl Acad Sci U S A, 2019 Mar 26. PMID 30867290, Free PMC Article
  2. Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif. Wang L, et al. Proc Natl Acad Sci U S A, 2014 Dec 30. PMID 25512493, Free PMC Article
  3. Transcription dependence and the roles of two excision repair pathways for UV damage in fission yeast Schizosaccharomyces pombe. Yasuhira S, et al. J Biol Chem, 1999 Sep 17. PMID 10480889
  4. Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines. Latypov VF, et al. Mol Cell, 2012 Jul 13. PMID 22658721, Free PMC Article
  5. Fission yeast homologs of human XPC and CSB, rhp41 and rhp26, are involved in transcription-coupled repair of methyl methanesulfonate-induced DNA damage. Kanamitsu K, et al. Genes Genet Syst, 2011. PMID 21670547

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. molecular basis of chromatin remodeling
    Title: Molecular basis of chromatin remodeling by Rhp26, a yeast CSB ortholog.
  2. The presence of the leucine latch motif in organisms ranging from yeast to humans suggests a conserved mechanism for the autoregulation of CSB/ERCC6 despite the otherwise highly divergent nature of the N- and C-terminal regions.
    Title: Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif.
  3. Fission yeast homologs of human XPC and CSB, rhp41 and rhp26, are involved in transcription-coupled repair of methyl methanesulfonate-induced DNA damage.
    Title: Fission yeast homologs of human XPC and CSB, rhp41 and rhp26, are involved in transcription-coupled repair of methyl methanesulfonate-induced DNA damage.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding ISM
Inferred from Sequence Model
more info
  
enables ATP hydrolysis activity IC
Inferred by Curator
more info
  
enables ATP-dependent chromatin remodeler activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in transcription-coupled nucleotide-excision repair IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription-coupled nucleotide-excision repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SNF2 family helicase Rhp26
NP_588091.1
  • SNF2 family DNA-dependent ATPase (human ERCC6) Rhp26

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1178932..1182638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023082.3 → NP_588091.1  SNF2 family helicase Rhp26 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588091.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9UR24
    Conserved Domains (3) summary
    COG0553
    Location:36 → 795
    HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
    cd00046
    Location:297 → 472
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:617 → 747
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
Nucleotide Protein
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