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spp27 RNA polymerase I upstream activation factor complex subunit Spp27 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539310, updated on 18-Sep-2024

Summary

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Official Symbol
spp27
Official Full Name
RNA polymerase I upstream activation factor complex subunit Spp27
Primary source
PomBase:SPCC285.17
Locus tag
SPOM_SPCC285.17
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
uaf30
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Genomic context

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See spp27 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003421.2 (1831983..1834169)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene TRAPP complex subunit Trs130 Neighboring gene 40S ribosomal protein eS28 Neighboring gene ncRNA Neighboring gene DNA mismatch repair protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin-protein ligase E3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the fission yeast ribosomal DNA binding factor: components share homology with Upstream Activating Factor and with SWI/SNF subunits. Liu M, et al. Nucleic Acids Res, 2002 Dec 15. PMID 12490702, Free PMC Article
  2. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
  3. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
  4. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
  5. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA polymerase I cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase I general transcription initiation factor activity IC
Inferred by Curator
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in nucleolar large rRNA transcription by RNA polymerase I IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription initiation at RNA polymerase I promoter EXP
Inferred from Experiment
more info
 PubMed 
involved_in transcription initiation at RNA polymerase I promoter IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of RNA polymerase I upstream activating factor complex EXP
Inferred from Experiment
more info
 PubMed 
part_of RNA polymerase I upstream activating factor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RNA polymerase I upstream activation factor complex subunit Spp27

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1831983..1834169
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023336.3 → NP_588345.1  RNA polymerase I upstream activation factor complex subunit Spp27 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588345.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74503
    Conserved Domains (3) summary
    COG5531
    Location:1 → 233
    Rsc6; Chromatin remodeling complex protein RSC6, contains SWIB domain [Chromatin structure and dynamics]
    pfam02201
    Location:119 → 191
    SWIB; SWIB/MDM2 domain
    pfam08766
    Location:2 → 52
    DEK_C; DEK C terminal domain
Nucleotide Protein
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