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hrr1 helicase Hrr1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539248, updated on 14-Nov-2024

Summary

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Official Symbol
hrr1
Official Full Name
helicase Hrr1
Primary source
PomBase:SPCC1739.03
Locus tag
SPOM_SPCC1739.03
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See hrr1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003421.2 (2029460..2034205)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene zf-CCCH type zinc finger protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein uL22m Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Dms1 Neighboring gene ncRNA Neighboring gene histone lysine methyltransferase Set5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A conserved ncRNA-binding protein recruits silencing factors to heterochromatin through an RNAi-independent mechanism. Marina DB, et al. Genes Dev, 2013 Sep 1. PMID 24013500, Free PMC Article
  2. Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Motamedi MR, et al. Cell, 2004 Dec 17. PMID 15607976
  3. Heterochromatin protein 1 homologue Swi6 acts in concert with Ers1 to regulate RNAi-directed heterochromatin assembly. Hayashi A, et al. Proc Natl Acad Sci U S A, 2012 Apr 17. PMID 22474355, Free PMC Article
  4. Conserved protein Pir2(ARS2) mediates gene repression through cryptic introns in lncRNAs. Thillainadesan G, et al. Nat Commun, 2020 May 15. PMID 32415063, Free PMC Article
  5. Ers1 links HP1 to RNAi. Rougemaille M, et al. Proc Natl Acad Sci U S A, 2012 Jul 10. PMID 22733737, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA helicase activity TAS
Traceable Author Statement
more info
 PubMed 
enables lncRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulatory ncRNA-mediated heterochromatin formation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in siRNA-mediated pericentric heterochromatin formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA-directed RNA polymerase complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
part_of nuclear RNA-directed RNA polymerase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of nuclear RNA-directed RNA polymerase complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
helicase Hrr1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    2029460..2034205
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023402.3 → NP_588411.2  helicase Hrr1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588411.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74465
    Conserved Domains (3) summary
    COG1112
    Location:158 → 965
    DNA2; Superfamily I DNA and/or RNA helicase [Replication, recombination and repair]
    pfam13087
    Location:757 → 942
    AAA_12; AAA domain
    pfam13245
    Location:387 → 446
    AAA_19; Part of AAA domain
Nucleotide Protein
Heading Accession and Version

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