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pxd1 protein Pdx1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539073, updated on 18-Sep-2024

Summary

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Official Symbol
pxd1
Official Full Name
protein Pdx1
Primary source
PomBase:SPCC1322.02
Locus tag
SPOM_SPCC1322.02
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See pxd1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (1286166..1287531)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 3' ssRNA-specific 3'-to-5' exonuclease Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene TRP-like ion channel protein Neighboring gene ncRNA Neighboring gene UTP-glucose-1-phosphate uridylyltransferase Neighboring gene aminopeptidase Lap2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel protein, Rsf1/Pxd1, is critical for the single-strand annealing pathway of double-strand break repair in Schizosaccharomyces pombe. Wang H, et al. Mol Microbiol, 2015 Jun. PMID 25777942
  2. CRL4Cdt2 ubiquitin ligase regulates Dna2 and Rad16 (XPF) nucleases by targeting Pxd1 for degradation. Zhang JM, et al. PLoS Genet, 2020 Jul. PMID 32692737, Free PMC Article
  3. Fission yeast Pxd1 promotes proper DNA repair by activating Rad16XPF and inhibiting Dna2. Zhang JM, et al. PLoS Biol, 2014 Sep. PMID 25203555, Free PMC Article
  4. Systematic localization study on novel proteins encoded by meiotically up-regulated ORFs in fission yeast. Ikebe C, et al. Biosci Biotechnol Biochem, 2011. PMID 22146723
  5. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Schizosaccharomyces pombe Pxd1 promotes proper DNA repair by activating Rad16XPF and inhibiting Dna2.
    Title: Fission yeast Pxd1 promotes proper DNA repair by activating Rad16XPF and inhibiting Dna2.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables endodeoxyribonuclease activator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA double-strand break processing IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in double-strand break repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in double-strand break repair via single-strand annealing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in gene conversion at mating-type locus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm HDA PubMed 
is_active_in cytosol HDA PubMed 
is_active_in mitotic spindle HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
protein Pdx1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1286166..1287531
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023120.3 → NP_588130.1  protein Pdx1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588130.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94542
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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