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sgf73 SAGA complex deubiquitinating submodule subunit Sgf73 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2538769, updated on 18-Sep-2024

Summary

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Official Symbol
sgf73
Official Full Name
SAGA complex deubiquitinating submodule subunit Sgf73
Primary source
PomBase:SPCC126.04c
Locus tag
SPOM_SPCC126.04C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See sgf73 in Genome Data Viewer
Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003421.2 (2122510..2123930, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA/U2 snRNA pseudouridine synthase Lsp1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein mL46 Neighboring gene ncRNA Neighboring gene twinfilin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Uncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity. Yan M, et al. J Mol Biol, 2015 Apr 24. PMID 25526805, Free PMC Article
  2. Sgf73, a subunit of SAGA complex, is required for the assembly of RITS complex in fission yeast. Deng X, et al. Sci Rep, 2015 Oct 7. PMID 26443059, Free PMC Article
  3. The SAGA histone acetyltransferase complex regulates leucine uptake through the Agp3 permease in fission yeast. Takahashi H, et al. J Biol Chem, 2012 Nov 2. PMID 22992726, Free PMC Article
  4. Histone H2B ubiquitination promotes the function of the anaphase-promoting complex/cyclosome in Schizosaccharomyces pombe. Elmore ZC, et al. G3 (Bethesda), 2014 Jun 19. PMID 24948786, Free PMC Article
  5. Mitotic spindle formation in the absence of Polo kinase. Kim J, et al. Proc Natl Acad Sci U S A, 2022 Mar 22. PMID 35286199, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Sgf73 plays important roles in chromatin modification, DNA damage repair and hyperoxia responses.
    Title: Large scale screening of genetic interaction with sgf73(+) in fission yeast.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
contributes_to cysteine-type deubiquitinase activity TAS
Traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
contributes_to transcription coactivator activity IC
Inferred by Curator
more info
  
Process Evidence Code Pubs
involved_in RITS complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in RITS complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II EXP
Inferred from Experiment
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulatory ncRNA-mediated heterochromatin formation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in siRNA-mediated pericentric heterochromatin formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transcription initiation-coupled chromatin remodeling IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of DUBm complex NAS
Non-traceable Author Statement
more info
  
part_of SAGA complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SAGA complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of SAGA complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
SAGA complex deubiquitinating submodule subunit Sgf73

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    2122510..2123930 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023438.3 → NP_588447.1  SAGA complex deubiquitinating submodule subunit Sgf73 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588447.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94397
    Conserved Domains (1) summary
    pfam08313
    Location:183 → 248
    SCA7; SCA7, zinc-binding domain
Nucleotide Protein
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Molecular Biology Databases
Research Materials