Rbp3 retinol binding protein 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rbp3provided by RGD
Official Full Name: retinol binding protein 3provided by RGD
Primary source: RGD:3545
See related: EnsemblRapid:ENSRNOG00000051911 AllianceGenome:RGD:3545
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Irbp
Summary: Enables retinol binding activity. Predicted to be involved in retinoid metabolic process. Located in interphotoreceptor matrix. Human ortholog(s) of this gene implicated in retinitis pigmentosa 66. Orthologous to human RBP3 (retinol binding protein 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Liver (RPKM 2.5), Brain (RPKM 1.5) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 16p16

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	16	NC_086034.1 (9273787..9282255)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	16	NC_051351.1 (9267538..9276006)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	16	NC_005115.4 (10277775..10286243)

Chromosome 16 - NC_086034.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

BE095712 (e-PCR)
- UniSTS:243511

Rbp3 (e-PCR), detects polymorphism
- UniSTS:536462

RH139342 (e-PCR)
- UniSTS:221428

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables retinol binding	IBA Inferred from Biological aspect of Ancestor more info
enables retinol binding	IDA Inferred from Direct Assay more info	PubMed
enables serine-type peptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in eye photoreceptor cell development	NAS Non-traceable Author Statement more info	PubMed
involved_in proteolysis	IEA Inferred from Electronic Annotation more info
involved_in retinoid metabolic process	IC Inferred by Curator more info	PubMed

Component	Evidence Code	Pubs
is_active_in cone matrix sheath	IBA Inferred from Biological aspect of Ancestor more info
located_in cone matrix sheath	ISO Inferred from Sequence Orthology more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
located_in interphotoreceptor matrix	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: retinol-binding protein 3

Names: interphotoreceptor retinoid binding protein; interphotoreceptor retinol- binding protein; retinol binding protein 3, interstitial; retinol-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.