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acox-1.3 Acyl-coenzyme A oxidase acox-1.3 [ Caenorhabditis elegans ]

Gene ID: 184167, updated on 2-Nov-2024

Summary

Official Symbol
acox-1.3
Official Full Name
Acyl-coenzyme A oxidase acox-1.3
Primary source
WormBase:WBGene00008566
Locus tag
CELE_F08A8.3
See related
AllianceGenome:WB:WBGene00008566
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Involved in ascaroside biosynthetic process and pheromone biosynthetic process. Predicted to be active in peroxisome. Human ortholog(s) of this gene implicated in Mitchell syndrome; congenital bile acid synthesis defect 6; and peroxisomal acyl-CoA oxidase deficiency. Orthologous to several human genes including ACOX1 (acyl-CoA oxidase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See acox-1.3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
8
Sequence:
Chromosome: I; NC_003279.8 (12946932..12951099)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Acyl-coenzyme A oxidase acox-1.1 Neighboring gene Acyl-coenzyme A oxidase acox-1.2 Neighboring gene Acyl-coenzyme A oxidase acox-1.4 Neighboring gene DUF2857 domain-containing protein Neighboring gene Galactoside 2-alpha-L-fucosyltransferase Neighboring gene ncRNA Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables FAD binding IEA
Inferred from Electronic Annotation
more info
 
enables acyl-CoA oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables acyl-CoA oxidase activity IEA
Inferred from Electronic Annotation
more info
 
enables fatty acid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables flavin adenine dinucleotide binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on the CH-CH group of donors IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in ascaroside biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ascaroside biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in fatty acid beta-oxidation IEA
Inferred from Electronic Annotation
more info
 
involved_in fatty acid beta-oxidation using acyl-CoA oxidase IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in fatty acid beta-oxidation using acyl-CoA oxidase IEA
Inferred from Electronic Annotation
more info
 
involved_in fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in pheromone biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Acyl-coenzyme A oxidase acox-1.3
NP_493263.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    12946932..12951099
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060862.3NP_493263.1  Acyl-coenzyme A oxidase acox-1.3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493263.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O62138
    Conserved Domains (1) summary
    cl09933
    Location:11634
    ACAD; Acyl-CoA dehydrogenase