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acd-3 DEgenerin Like [ Caenorhabditis elegans ]

Gene ID: 182963, updated on 2-Nov-2024

Summary

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Official Symbol
acd-3
Official Full Name
DEgenerin Like
Primary source
WormBase:WBGene00007775
Locus tag
CELE_C27C12.5
See related
AllianceGenome:WB:WBGene00007775
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in intestine. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See acd-3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
13
Sequence:
Chromosome: X; NC_003284.9 (14849275..14852631)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Dipeptidyl peptidase family member 2 Neighboring gene Early growth response factor homolog 1 Neighboring gene E3 ubiquitin-protein ligase LIN-1 Neighboring gene UNC93-like protein MFSD11 Neighboring gene Doublesex- and mab-3-related transcription factor dmd-4 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Distinct roles for two Caenorhabditis elegans acid-sensing ion channels in an ultradian clock. Kaulich E, et al. Elife, 2022 Jun 6. PMID 35666106, Free PMC Article
  2. Physiological insight into the conserved properties of Caenorhabditis elegans acid-sensing degenerin/epithelial sodium channels. Kaulich E, et al. J Physiol, 2023 May. PMID 36200489, Free PMC Article
  3. A proprioceptive feedback circuit drives Caenorhabditis elegans locomotor adaptation through dopamine signaling. Ji H, et al. Proc Natl Acad Sci U S A, 2023 May 16. PMID 37155851, Free PMC Article
  4. Locomotion modulates olfactory learning through proprioception in C. elegans. Zhan X, et al. Nat Commun, 2023 Jul 27. PMID 37500635, Free PMC Article
  5. Mechanosensation. Goodman MB. WormBook, 2006 Jan 6. PMID 18050466, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ligand-gated sodium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sodium channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DEgenerin Like
NP_001257250.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    14849275..14852631
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001270321.3 → NP_001257250.1  DEgenerin Like [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257250.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G3MU02
    Conserved Domains (1) summary
    pfam00858
    Location:33 → 382
    ASC; Amiloride-sensitive sodium channel
Nucleotide Protein
Heading Accession and Version

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