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pigc-1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit C [ Caenorhabditis elegans ]

Gene ID: 177765, updated on 18-Sep-2024

Summary

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Official Symbol
pigc-1
Official Full Name
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
Primary source
WormBase:WBGene00011860
Locus tag
CELE_T20D3.8
See related
AllianceGenome:WB:WBGene00011860
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable glycosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human PIGC (phosphatidylinositol glycan anchor biosynthesis class C). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See pigc-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
5
Sequence:
Chromosome: IV; NC_003282.8 (9341964..9343152, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene HIG1 domain-containing protein Neighboring gene Vacuolar protein sorting-associated protein 26 Neighboring gene Piezo-type mechanosensitive ion channel component 1 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
NP_501645.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    9341964..9343152 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069244.4 → NP_501645.1  Phosphatidylinositol N-acetylglucosaminyltransferase subunit C [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501645.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01259
    Conserved Domains (1) summary
    pfam06432
    Location:7 → 273
    GPI2; Phosphatidylinositol N-acetylglucosaminyltransferase
Nucleotide Protein
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