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far-2 Fatty-acid and retinol-binding protein 2 [ Caenorhabditis elegans ]

Gene ID: 176284, updated on 18-Sep-2024

Summary

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Official Symbol
far-2
Official Full Name
Fatty-acid and retinol-binding protein 2
Primary source
WormBase:WBGene00001386
Locus tag
CELE_F02A9.3
See related
AllianceGenome:WB:WBGene00001386
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable fatty acid binding activity and retinol binding activity. Predicted to be located in extracellular region. Is expressed in body wall musculature; vulval muscle; and in male. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See far-2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003281.10 (9081828..9082511)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Large ribosomal subunit protein mL44 Neighboring gene putative methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Neighboring gene glp-1/Notch intracellular domain Neighboring gene Putative serine/threonine-protein kinase ZK507.1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils. Zhan B, et al. PLoS Negl Trop Dis, 2018 Oct. PMID 30296268, Free PMC Article
  2. Caenorhabditis elegans reporter fusion genes generated by seamless modification of large genomic DNA clones. Dolphin CT, et al. Nucleic Acids Res, 2006 May 22. PMID 16717278, Free PMC Article
  3. The FAR proteins of parasitic nematodes: their possible involvement in the pathogenesis of infection and the use of Caenorhabditis elegans as a model system to evaluate their function. Garofalo A, et al. Med Microbiol Immunol, 2003 Feb. PMID 12592563
  4. 'Promoter trapping' in Caenorhabditis elegans. Hope IA. Development, 1991 Oct. PMID 1782857
  5. Differences in protein expression associated with ivermectin resistance in Caenorhabditis elegans. Sousa DM, et al. Rev Bras Parasitol Vet, 2019 Jan-Mar. PMID 30916256

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables fatty acid binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
enables retinol binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Fatty-acid and retinol-binding protein 2
NP_499011.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    9081828..9082511
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066610.8 → NP_499011.1  Fatty-acid and retinol-binding protein 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499011.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34383
    Conserved Domains (1) summary
    pfam05823
    Location:33 → 174
    Gp-FAR-1; Nematode fatty acid retinoid binding protein (Gp-FAR-1)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34383.1

Gene LinkOut

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