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ceeh-1 Epoxide hydrolase 1 [ Caenorhabditis elegans ]

Gene ID: 175239, updated on 18-Sep-2024

Summary

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Official Symbol
ceeh-1
Official Full Name
Epoxide hydrolase 1
Primary source
WormBase:WBGene00019329
Locus tag
CELE_K02F3.6
See related
AllianceGenome:WB:WBGene00019329
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables epoxide hydrolase activity. Involved in cellular lipid metabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human EPHX3 (epoxide hydrolase 3) and EPHX4 (epoxide hydrolase 4). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See ceeh-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003281.10 (828593..832277, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Dachshund homolog dac-1 Neighboring gene ncRNA Neighboring gene C-type lectin domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of two epoxide hydrolases in Caenorhabditis elegans that metabolize mammalian lipid signaling molecules. Harris TR, et al. Arch Biochem Biophys, 2008 Apr 15. PMID 18267101, Free PMC Article
  2. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables epoxide hydrolase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables epoxide hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cellular lipid metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Epoxide hydrolase 1
NP_497268.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    828593..832277 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064867.7 → NP_497268.1  Epoxide hydrolase 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497268.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EBI4
    Conserved Domains (2) summary
    COG0596
    Location:119 → 400
    MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
    cl21494
    Location:128 → 257
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
G5EBI4.1

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