cox-17 Cytochrome c oxidase copper chaperone [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: cox-17
Official Full Name: Cytochrome c oxidase copper chaperone
Primary source: WormBase:WBGene00018240
Locus tag: CELE_F40G9.2
See related: AllianceGenome:WB:WBGene00018240
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable copper chaperone activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be active in mitochondrial intermembrane space. Is expressed in body wall musculature; intestine; and reproductive system. Orthologous to human COX17 (cytochrome c oxidase copper chaperone COX17). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cox-17 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 2

Sequence:: Chromosome: III; NC_003281.10 (190986..191981)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

STS3-101 (e-PCR)
- UniSTS:241938

F40G9.2 (e-PCR)
- UniSTS:320539

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables copper chaperone activity	IBA Inferred from Biological aspect of Ancestor more info
enables copper chaperone activity	IEA Inferred from Electronic Annotation more info
enables copper ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mitochondrial cytochrome c oxidase assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrial intermembrane space	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial intermembrane space	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Cytochrome c oxidase copper chaperone

NP_497175.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

190986..191981

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_064774.5 → NP_497175.1 Cytochrome c oxidase copper chaperone [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_497175.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9TZ68

Conserved Domains (1) summary

pfam05051
Location:18 → 63

COX17; Cytochrome C oxidase copper chaperone (COX17)