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pigm-1 GPI mannosyltransferase 1 [ Caenorhabditis elegans ]

Gene ID: 174736, updated on 2-Nov-2024

Summary

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Official Symbol
pigm-1
Official Full Name
GPI mannosyltransferase 1
Primary source
WormBase:WBGene00007189
Locus tag
CELE_B0491.1
See related
AllianceGenome:WB:WBGene00007189
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable mannosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of glycosylphosphatidylinositol-mannosyltransferase I complex. Orthologous to human PIGM (phosphatidylinositol glycan anchor biosynthesis class M). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pigm-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (11348445..11350057)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Complex I-B14.7 Neighboring gene DNA helicase Neighboring gene diphthine methyl ester synthase Neighboring gene Chloride channel protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables alpha-1,4-mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycolipid mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in GPI anchor metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
part_of glycosylphosphatidylinositol-mannosyltransferase I complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GPI mannosyltransferase 1
NP_496426.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    11348445..11350057
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064025.6 → NP_496426.1  GPI mannosyltransferase 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496426.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q17515
    Conserved Domains (1) summary
    pfam05007
    Location:146 → 405
    Mannosyl_trans; Mannosyltransferase (PIG-M)
Nucleotide Protein
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