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F07F6.8 Apolipoprotein L3-like [ Caenorhabditis elegans ]

Gene ID: 173926, updated on 18-Sep-2024

Summary

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Official Symbol
F07F6.8
Official Full Name
Apolipoprotein L3-like
Primary source
WormBase:WBGene00017220
Locus tag
CELE_F07F6.8
See related
AllianceGenome:WB:WBGene00017220
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable lipid binding activity. Predicted to be involved in lipid transport and lipoprotein metabolic process. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis and schizophrenia. Orthologous to several human genes including APOL3 (apolipoprotein L3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See F07F6.8 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (5424141..5425733, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene PHR domain-containing protein Neighboring gene ncRNA Neighboring gene Embryonic developmental protein tofu-6 Neighboring gene Apolipoprotein L, 1 Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene 7TM GPCR serpentine receptor class x (Srx) domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables lipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in lipoprotein metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Apolipoprotein L3-like
NP_001379858.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    5424141..5425733 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001393070.1 → NP_001379858.1  Apolipoprotein L3-like [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8WQF7
    Conserved Domains (1) summary
    pfam05461
    Location:59 → 126
    ApoL; Apolipoprotein L
Nucleotide Protein
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