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pigu-1 GPI transamidase component GAB1 [ Caenorhabditis elegans ]

Gene ID: 172565, updated on 19-Jun-2024

Summary

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Gene symbol
pigu-1
Gene description
GPI transamidase component GAB1
Locus tag
CELE_T22C1.3
See related
AllianceGenome:WB:WBGene00011914
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in attachment of GPI anchor to protein and protein localization to cell surface. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be part of GPI-anchor transamidase complex. Orthologous to human PIGU (phosphatidylinositol glycan anchor biosynthesis class U). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See pigu-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
6
Sequence:
Chromosome: I; NC_003279.8 (7938560..7940144)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Myosin-11 Neighboring gene UBR-type domain-containing protein Neighboring gene Globin-like protein 26 Neighboring gene Ctf8 Neighboring gene TFIIIC_sub6 domain-containing protein Neighboring gene Transport and Golgi organization protein 1 homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in attachment of GPI anchor to protein IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in attachment of GPI anchor to protein IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of GPI-anchor transamidase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of GPI-anchor transamidase complex IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GPI transamidase component GAB1
NP_492189.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    7938560..7940144
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059788.6 → NP_492189.2  GPI transamidase component GAB1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492189.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22672
    Conserved Domains (1) summary
    pfam06728
    Location:32 → 382
    PIG-U; GPI transamidase subunit PIG-U
Nucleotide Protein
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