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coq-1 Decaprenyl-diphosphate synthase subunit 2 [ Caenorhabditis elegans ]

Gene ID: 172190, updated on 2-Nov-2024

Summary

Official Symbol
coq-1
Official Full Name
Decaprenyl-diphosphate synthase subunit 2
Primary source
WormBase:WBGene00000761
Locus tag
CELE_C24A11.9
See related
AllianceGenome:WB:WBGene00000761
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable prenyltransferase activity. Involved in ubiquinone biosynthetic process. Predicted to be extrinsic component of mitochondrial inner membrane. Predicted to be part of polyprenyl diphosphate synthase complex. Predicted to be active in mitochondrion. Is expressed in intestine. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 2. Orthologous to human PDSS1 (decaprenyl diphosphate synthase subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See coq-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
11
Sequence:
Chromosome: I; NC_003279.8 (5412841..5415629, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene FERM domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Thioredoxin domain-containing protein Neighboring gene Small-subunit processome Neighboring gene uncharacterized protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables prenyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity, transferring alkyl or aryl (other than methyl) groups ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
involved_in isoprenoid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in isoprenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in pheromone biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in ubiquinone biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ubiquinone biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in extrinsic component of mitochondrial inner membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of polyprenyl diphosphate synthase complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Decaprenyl-diphosphate synthase subunit 2
NP_491588.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    5412841..5415629 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059187.6NP_491588.1  Decaprenyl-diphosphate synthase subunit 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491588.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    P91093
    Conserved Domains (1) summary
    pfam00348
    Location:80344
    polyprenyl_synt; Polyprenyl synthetase