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NP nucleocapsid protein [ Mumps orthorubulavirus ]

Gene ID: 1489766, updated on 18-Aug-2023

Summary

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Gene symbol
NP
Gene description
nucleocapsid protein
Locus tag
MuVgp1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mumps orthorubulavirus (strain: Miyahara)
Lineage
Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina; Monjiviricetes; Mononegavirales; Paramyxoviridae; Rubulavirinae; Orthorubulavirus
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Genomic context

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Sequence:
NC_002200.1 (146..1795)

NC_002200.1Genomic Context describing neighboring genes Neighboring gene V protein;phoshoprotein Neighboring gene membrane protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002200.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Roles of Phosphorylation of the Nucleocapsid Protein of Mumps Virus in Regulating Viral RNA Transcription and Replication. Zengel J, et al. J Virol, 2015 Jul. PMID 25948749, Free PMC Article
  2. Variability of hemagglutinin-neuraminidase and nucleocapsid protein of vaccine and wild-type mumps virus strains. Ivancic-Jelecki J, et al. Infect Genet Evol, 2008 Sep. PMID 18508415
  3. Mumps Virus Nucleoprotein Enhances Phosphorylation of the Phosphoprotein by Polo-Like Kinase 1. Pickar A, et al. J Virol, 2016 Feb 1. PMID 26608325, Free PMC Article
  4. Mumps virus matrix, fusion, and nucleocapsid proteins cooperate for efficient production of virus-like particles. Li M, et al. J Virol, 2009 Jul. PMID 19439476, Free PMC Article
  5. Molecular cloning and sequence analysis of the mumps virus gene encoding the L protein and the trailer sequence. Okazaki K, et al. Virology, 1992 Jun. PMID 1585659

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The authers have identified the serine/threonine kinase Polo-like kinase 1 (PLK1) as a host kinase that phosphorylates mumps virus P and have found that phosphorylation of P by PLK1 is enhanced by mumps virus NP.
    Title: Mumps Virus Nucleoprotein Enhances Phosphorylation of the Phosphoprotein by Polo-Like Kinase 1.
  2. The S439 is the major phosphorylation site of NP and its phosphorylation plays an important role in downregulating viral RNA synthesis.
    Title: Roles of Phosphorylation of the Nucleocapsid Protein of Mumps Virus in Regulating Viral RNA Transcription and Replication.
  3. Mumps virus matrix, fusion, and nucleocapsid proteins cooperate together for efficient particle production.
    Title: Mumps virus matrix, fusion, and nucleocapsid proteins cooperate for efficient production of virus-like particles.
  4. the highest mean percentage of amino acid differences in both hemagglutinin-neuraminidase and nucleocapsid protein was found for Jeryl Lynn 5 and Jeryl Lynn 2 strains while the lowest value was obtained for Leningrad-3 and L-Zagreb strains
    Title: Variability of hemagglutinin-neuraminidase and nucleocapsid protein of vaccine and wild-type mumps virus strains.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
nucleocapsid protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002200.1 Reference assembly

    Range
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_054707.1 nucleocapsid protein [Mumps orthorubulavirus]

    See identical proteins and their annotated locations for NP_054707.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P21186, Q783W2
    UniProtKB/TrEMBL
    M1UZJ4, M1VNX9
    Conserved Domains (1) summary
    pfam00973
    Location:1 → 406
    Paramyxo_ncap; Paramyxovirus nucleocapsid protein
Nucleotide Protein
Heading Accession and Version

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