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ORF37 envelope glycoprotein H [ Human alphaherpesvirus 3 (Varicella-zoster virus) ]

Gene ID: 1487668, updated on 18-Aug-2023

Summary

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Gene symbol
ORF37
Gene description
envelope glycoprotein H
Locus tag
HHV3_gp39
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Human alphaherpesvirus 3 (strain: Dumas, acronym: HHV-3, acronym: VZV, nat-host: Homo sapiens)
Lineage
Viruses; dsDNA viruses, no RNA stage; Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus
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Genomic context

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Sequence:
NC_001348.1 (66074..68616)

NC_001348.1Genomic Context describing neighboring genes Neighboring gene capsid scaffold protein Neighboring gene capsid maturation protease Neighboring gene DNA packaging tegument protein UL25 Neighboring gene nuclear protein UL24 Neighboring gene thymidine kinase Neighboring gene tegument protein UL21 Neighboring gene envelope protein UL20

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001348.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Glycoprotein B Cytoplasmic Domain Lysine Cluster Is Critical for Varicella-Zoster Virus Cell-Cell Fusion Regulation and Infection. Yang E, et al. J Virol, 2017 Jan 1. PMID 27795427, Free PMC Article
  2. Incorporation of three endocytosed varicella-zoster virus glycoproteins, gE, gH, and gB, into the virion envelope. Maresova L, et al. J Virol, 2005 Jan. PMID 15613328, Free PMC Article
  3. The complete DNA sequence of varicella-zoster virus. Davison AJ, et al. J Gen Virol, 1986 Sep. PMID 3018124

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Effective Varicella-Zoster virus propagation is dependent on cell-cell fusion regulation by the conserved glycoprotein B lysine cluster, in addition to the immunoreceptor tyrosine-based inhibition motif and the glycoprotein H.
    Title: The Glycoprotein B Cytoplasmic Domain Lysine Cluster Is Critical for Varicella-Zoster Virus Cell-Cell Fusion Regulation and Infection.
  2. Incorporation of three endocytosed varicella-zoster virus glycoproteins, gE, gH, and gB, into the virion envelope.
    Title: Incorporation of three endocytosed varicella-zoster virus glycoproteins, gE, gH, and gB, into the virion envelope.
Submit: New GeneRIF Correction

General gene information

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Homology

regulatory

  • Loc: 68611-68616 regulatory_class = polyA_signal_sequence

General protein information

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Preferred Names
envelope glycoprotein H
NP_040160.1

VOG classification

Description:

  • VOGd0072 [A] Glycoprotein H
  • Auxilary Proteins

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001348.1 Reference assembly

    Range
    66074..68616
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_040160.1 envelope glycoprotein H [Human alphaherpesvirus 3]

    See identical proteins and their annotated locations for NP_040160.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P09260
    UniProtKB/TrEMBL
    G9IY38, Q6YPA5, Q77JF9, Q77JX2
    Conserved Domains (1) summary
    PHA03294
    Location:1 → 835
    PHA03294; envelope glycoprotein H; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
1306448A.1
CAA27920.1

Gene LinkOut

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