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ipaC IpaC, secreted by the Mxi-Spa secretion machinery, required for entry into epithelial cells [ Shigella flexneri 2a str. 301 ]

Gene ID: 1238054, updated on 6-Jun-2024

Summary

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Gene symbol
ipaC
Gene description
IpaC, secreted by the Mxi-Spa secretion machinery, required for entry into epithelial cells
Locus tag
CP0127
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Shigella flexneri 2a str. 301 (strain: 301, serotype: 2a)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
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Genomic context

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Location:
plasmid: pCP301
Sequence:
NC_004851.1 (110137..111228, complement)

NC_004851.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene IpaB, secreted by the Mxi-Spa secretion machinery, required for entry into epithelial cells Neighboring gene IpgC, cytoplasmic chaperone for IpaB and IpaC

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004851.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of RanBMP interacting with Shigella flexneri IpaC invasin by two-hybrid system of yeast. Yao X, et al. World J Gastroenterol, 2003 Jun. PMID 12800254, Free PMC Article
  2. Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Jin Q, et al. Nucleic Acids Res, 2002 Oct 15. PMID 12384590, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General protein information

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Names
IpaC, secreted by the Mxi-Spa secretion machinery, required for entry into epithelial cells

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004851.1 Reference assembly

    Range
    110137..111228 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_858260.2 IpaC, secreted by the Mxi-Spa secretion machinery, required for entry into epithelial cells [Shigella flexneri 2a str. 301]

    See identical proteins and their annotated locations for NP_858260.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    F5P4J9
    Conserved Domains (1) summary
    PRK15373
    Location:1 → 363
    PRK15373; IpaC/SipC family type III secretion system needle tip complex protein
Nucleotide Protein
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