U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OR10AD1 olfactory receptor family 10 subfamily AD member 1 [ Homo sapiens (human) ]

Gene ID: 121275, updated on 2-Nov-2024

Summary

Official Symbol
OR10AD1provided by HGNC
Official Full Name
olfactory receptor family 10 subfamily AD member 1provided by HGNC
Primary source
HGNC:HGNC:14819
See related
Ensembl:ENSG00000172640 AllianceGenome:HGNC:14819
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR12-1; OR10AD1P
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR10AD1 in Genome Data Viewer
Location:
12q13.11
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (48202339..48203292, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (48163697..48164650, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (48596122..48597075, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene endoplasmic reticulum oxidoreductase 1 alpha pseudogene Neighboring gene coiled-coil domain containing 184 Neighboring gene uncharacterized LOC102725258 Neighboring gene MPRA-validated peak1716 silencer Neighboring gene uncharacterized LOC105369753 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:48723521-48724020 Neighboring gene H1.7 linker histone

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
olfactory receptor 10AD1
Names
olfactory receptor OR12-1
olfactory receptor, family 10, subfamily AD, member 1 pseudogene

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004134.1NP_001004134.1  olfactory receptor 10AD1

    See identical proteins and their annotated locations for NP_001004134.1

    Status: PROVISIONAL

    Source sequence(s)
    AB065872
    Consensus CDS
    CCDS31787.1
    UniProtKB/Swiss-Prot
    B9EGT9, Q6IFA8, Q8NGE0
    UniProtKB/TrEMBL
    A0A126GWC9
    Related
    ENSP00000308689.2, ENST00000310248.4
    Conserved Domains (2) summary
    pfam00001
    Location:42291
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:35306
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    48202339..48203292 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    48163697..48164650 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)