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NR5A1 nuclear receptor subfamily 5 group A member 1 [ Canis lupus familiaris (dog) ]

Gene ID: 119863935, updated on 21-Mar-2024

Summary

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Gene symbol
NR5A1
Gene description
nuclear receptor subfamily 5 group A member 1
See related
Ensembl:ENSCAFG00845010545
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
SF-1; Ad4BP
Orthologs
human mouse all
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Genomic context

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See NR5A1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (59379513..59404555)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (57657456..57682377)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (58545169..58570064)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (58138376..58163298)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (58454658..58479575)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor subfamily 6 group A member 1 Neighboring gene uncharacterized LOC102152471 Neighboring gene microRNA mir-181a-2 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC102151918 Neighboring gene adhesion G-protein coupled receptor D2 Neighboring gene adhesion G protein-coupled receptor D2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Screening for structural variants of four candidate genes in dogs with disorders of sex development revealed the first case of a large deletion in NR5A1. Nowacka-Woszuk J, et al. Anim Reprod Sci, 2020 Dec. PMID 33128907
  2. Dog Steroidogenic Factor-1: Molecular cloning and analysis of epigenetic regulation. Sekiya A, et al. J Vet Med Sci, 2020 Jun 16. PMID 32238671, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Screening for structural variants of four candidate genes in dogs with disorders of sex development revealed the first case of a large deletion in NR5A1.
    Title: Screening for structural variants of four candidate genes in dogs with disorders of sex development revealed the first case of a large deletion in NR5A1.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in hormone-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tissue development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA polymerase II transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
steroidogenic factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    59379513..59404555
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038678622.1 → XP_038534550.1  steroidogenic factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KST5, A0A8C0PTC6, A0A8I3NFB8, A0A8P0SNZ9
    Conserved Domains (2) summary
    cd07070
    Location:233 → 469
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:23 → 115
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

  2. XM_038678624.1 → XP_038534552.1  steroidogenic factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A5K7W231, A0A8C0KST5, A0A8C0PTC6, A0A8C0PXM8, A0A8C0R1X0, A0A8I3NFB8
    Related
    ENSCAFP00845014498.1, ENSCAFT00845018582.1
    Conserved Domains (2) summary
    cd07070
    Location:223 → 459
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:13 → 105
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

  3. XM_038678625.1 → XP_038534553.1  steroidogenic factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A5K7W231, A0A8C0KST5, A0A8C0PTC6, A0A8C0PXM8, A0A8C0R1X0, A0A8I3NFB8
    Conserved Domains (2) summary
    cd07070
    Location:223 → 459
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:13 → 105
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    58138376..58163298
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038487453.1 → XP_038343381.1  steroidogenic factor 1 isoform X1

    Conserved Domains (2) summary
    cd07070
    Location:233 → 469
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:23 → 115
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

  2. XM_038487454.1 → XP_038343382.1  steroidogenic factor 1 isoform X2

    Conserved Domains (2) summary
    cd07070
    Location:223 → 459
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:13 → 105
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

  3. XM_038487455.1 → XP_038343383.1  steroidogenic factor 1 isoform X2

    Conserved Domains (2) summary
    cd07070
    Location:223 → 459
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:13 → 105
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    58454658..58479575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038613330.1 → XP_038469258.1  steroidogenic factor 1 isoform X1

    Conserved Domains (2) summary
    cd07070
    Location:233 → 469
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:23 → 115
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

  2. XM_038613331.1 → XP_038469259.1  steroidogenic factor 1 isoform X2

    Conserved Domains (2) summary
    cd07070
    Location:223 → 459
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:13 → 105
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

  3. XM_038613332.1 → XP_038469260.1  steroidogenic factor 1 isoform X2

    Conserved Domains (2) summary
    cd07070
    Location:223 → 459
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:13 → 105
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    58545169..58570064
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038549390.1 → XP_038405318.1  steroidogenic factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KST5, A0A8C0PTC6, A0A8I3NFB8, A0A8P0SNZ9
    Conserved Domains (2) summary
    cd07070
    Location:233 → 469
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:23 → 115
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

  2. XM_038549391.1 → XP_038405319.1  steroidogenic factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A5K7W231, A0A8C0KST5, A0A8C0PTC6, A0A8C0PXM8, A0A8C0R1X0, A0A8I3NFB8
    Conserved Domains (2) summary
    cd07070
    Location:223 → 459
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:13 → 105
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

  3. XM_038549392.1 → XP_038405320.1  steroidogenic factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A5K7W231, A0A8C0KST5, A0A8C0PTC6, A0A8C0PXM8, A0A8C0R1X0, A0A8I3NFB8
    Conserved Domains (2) summary
    cd07070
    Location:223 → 459
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:13 → 105
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    57657456..57682377
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038620169.1 → XP_038476097.1  steroidogenic factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KST5, A0A8C0PTC6, A0A8I3NFB8, A0A8P0SNZ9
    Conserved Domains (2) summary
    cd07070
    Location:233 → 469
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:23 → 115
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

  2. XM_038620175.1 → XP_038476103.1  steroidogenic factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A5K7W231, A0A8C0KST5, A0A8C0PTC6, A0A8C0PXM8, A0A8C0R1X0, A0A8I3NFB8
    Conserved Domains (2) summary
    cd07070
    Location:223 → 459
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:13 → 105
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers

  3. XM_038620176.1 → XP_038476104.1  steroidogenic factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A5K7W231, A0A8C0KST5, A0A8C0PTC6, A0A8C0PXM8, A0A8C0R1X0, A0A8I3NFB8
    Conserved Domains (2) summary
    cd07070
    Location:223 → 459
    NR_LBD_SF-1; The ligand binding domain of nuclear receptor steroidogenic factor 1, a member of nuclear receptor superfamily
    cd07167
    Location:13 → 105
    NR_DBD_Lrh-1_like; The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers
Nucleotide Protein
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