Nrxn3 neurexin 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 116508, updated on 14-Nov-2024

Summary

Go to the top of the page Help

Symbol: Nrxn3provided by RGD
Full Name: neurexin 3provided by RGD
Primary source: RGD:620212
See related: EnsemblRapid:ENSRNOG00000047574 AllianceGenome:RGD:620212
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable calcium channel regulator activity. Predicted to be involved in several processes, including modulation of chemical synaptic transmission; neurotransmitter receptor localization to postsynaptic specialization membrane; and postsynaptic density assembly. Predicted to act upstream of or within neurotransmitter secretion and synapse assembly. Predicted to be located in cell projection and presynaptic membrane. Predicted to be part of protein-containing complex. Predicted to be active in GABA-ergic synapse; glutamatergic synapse; and presynaptic active zone membrane. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human NRXN3 (neurexin 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward (RPKM 214.5) See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See Nrxn3 in Genome Data Viewer

Location:: 6q31

Exon count:: 31

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (113372667..115004073)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (107641760..109272849)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (112133204..114069589)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data show beta-cell expression of the neurexin 3, and demonstrate that the neurexins are expressed outside the central nervous system and help confer an inhibitory synaptic-like phenotype onto the beta-cell surface.
Title: Expression of neurexin, neuroligin, and their cytoplasmic binding partners in the pancreatic beta-cells and the involvement of neuroligin in insulin secretion.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

RH144490 (e-PCR)
- UniSTS:233735

BE108622 (e-PCR)
- UniSTS:247821

D6Got200 (e-PCR)
- UniSTS:115996

D6Got145 (e-PCR)
- UniSTS:115236

D6Got144 (e-PCR)
- UniSTS:113191

RH128451 (e-PCR)
- UniSTS:211759

D6Got155 (e-PCR)
- UniSTS:113459

AW530543 (e-PCR)
- UniSTS:244532

D6Got149 (e-PCR)
- UniSTS:113470

RH138907 (e-PCR)
- UniSTS:220994

BE102650 (e-PCR)
- UniSTS:244296

RH144567 (e-PCR)
- UniSTS:233812

BE108105 (e-PCR)
- UniSTS:247641

BE115279 (e-PCR)
- UniSTS:261472

AU048299 (e-PCR)
- UniSTS:109673

BE117867 (e-PCR)
- UniSTS:248725

d6rat66 (e-PCR)
- UniSTS:122261

BF416388 (e-PCR)
- UniSTS:249266

BE115916 (e-PCR)
- UniSTS:248243

BF386965 (e-PCR)
- UniSTS:243898

D6Got147 (e-PCR)
- UniSTS:115387

D6Rat191 (e-PCR)
- UniSTS:228029

D6Rat48 (e-PCR)
- UniSTS:118978

BF391590 (e-PCR)
- UniSTS:249805

D6Rat216 (e-PCR), detects polymorphism
- UniSTS:228053

AU047113 (e-PCR)
- UniSTS:110828

D6Got150 (e-PCR)
- UniSTS:112380

BE101757 (e-PCR)
- UniSTS:243708

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables calcium channel regulator activity	IEA Inferred from Electronic Annotation more info
enables calcium channel regulator activity	ISO Inferred from Sequence Orthology more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in adult behavior	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chemical synaptic transmission	ISO Inferred from Sequence Orthology more info
involved_in learning	ISO Inferred from Sequence Orthology more info
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane	IEA Inferred from Electronic Annotation more info
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane	ISO Inferred from Sequence Orthology more info
involved_in neurotransmitter secretion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within neurotransmitter secretion	ISO Inferred from Sequence Orthology more info
involved_in postsynaptic density assembly	IEA Inferred from Electronic Annotation more info
involved_in postsynaptic density assembly	ISO Inferred from Sequence Orthology more info
involved_in presynaptic modulation of chemical synaptic transmission	IEA Inferred from Electronic Annotation more info
involved_in presynaptic modulation of chemical synaptic transmission	ISO Inferred from Sequence Orthology more info
involved_in regulation of postsynaptic membrane neurotransmitter receptor levels	ISO Inferred from Sequence Orthology more info
involved_in social behavior	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within synapse assembly	ISO Inferred from Sequence Orthology more info
involved_in trans-synaptic signaling	ISO Inferred from Sequence Orthology more info
involved_in trans-synaptic signaling, modulating synaptic transmission	IEA Inferred from Electronic Annotation more info
involved_in trans-synaptic signaling, modulating synaptic transmission	ISO Inferred from Sequence Orthology more info
involved_in vocalization behavior	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in GABA-ergic synapse	IEA Inferred from Electronic Annotation more info
is_active_in GABA-ergic synapse	ISO Inferred from Sequence Orthology more info
located_in cell junction	IEA Inferred from Electronic Annotation more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in glutamatergic synapse	IEA Inferred from Electronic Annotation more info
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
located_in presynaptic active zone membrane	IEA Inferred from Electronic Annotation more info
is_active_in presynaptic active zone membrane	ISO Inferred from Sequence Orthology more info
located_in presynaptic membrane	IEA Inferred from Electronic Annotation more info
located_in presynaptic membrane	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	IEA Inferred from Electronic Annotation more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info
part_of trans-synaptic protein complex	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: neurexin-3

Names: neurexin III

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053817.3 → NP_446269.3 neurexin-3 precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000006

UniProtKB/TrEMBL

D3ZKS5

Related

ENSRNOP00000060600.5, ENSRNOT00000064872.5

Conserved Domains (6) summary

smart00282
Location:286 → 417

LamG; Laminin G domain

cd00054
Location:651 → 684

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1504 → 1539

Syndecan; Syndecan domain

pfam02210
Location:903 → 1031

Laminin_G_2; Laminin G domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086024.1 Reference GRCr8

Range

113372667..115004073

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039111661.2 → XP_038967589.1 neurexin-3 isoform X46

UniProtKB/TrEMBL

A0A8I6GKC4

Conserved Domains (6) summary

smart00282
Location:266 → 405

LamG; Laminin G domain

cd00054
Location:639 → 672

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1343 → 1378

Syndecan; Syndecan domain

pfam02210
Location:882 → 1010

Laminin_G_2; Laminin G domain
XM_063261446.1 → XP_063117516.1 neurexin-3 isoform X27
XM_063261447.1 → XP_063117517.1 neurexin-3 isoform X28

Related

ENSRNOP00000089493.2, ENSRNOT00000092573.3
XM_063261425.1 → XP_063117495.1 neurexin-3 isoform X1
XM_039111627.2 → XP_038967555.1 neurexin-3 isoform X1

UniProtKB/TrEMBL

A0A8I6GKL9

Conserved Domains (6) summary

smart00282
Location:282 → 421

LamG; Laminin G domain

cd00054
Location:655 → 688

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1618 → 1653

Syndecan; Syndecan domain

pfam02210
Location:907 → 1035

Laminin_G_2; Laminin G domain
XM_063261433.1 → XP_063117503.1 neurexin-3 isoform X11
XM_063261440.1 → XP_063117510.1 neurexin-3 isoform X20
XM_063261427.1 → XP_063117497.1 neurexin-3 isoform X2
XM_063261434.1 → XP_063117504.1 neurexin-3 isoform X12
XM_063261441.1 → XP_063117511.1 neurexin-3 isoform X21
XM_063261431.1 → XP_063117501.1 neurexin-3 isoform X9
XM_063261428.1 → XP_063117498.1 neurexin-3 isoform X4
XM_063261442.1 → XP_063117512.1 neurexin-3 isoform X22
XM_039111656.2 → XP_038967584.1 neurexin-3 isoform X36

UniProtKB/TrEMBL

D3ZKS5

Conserved Domains (6) summary

smart00282
Location:282 → 421

LamG; Laminin G domain

cd00054
Location:655 → 688

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1398 → 1433

Syndecan; Syndecan domain

pfam02210
Location:907 → 1035

Laminin_G_2; Laminin G domain
XM_063261432.1 → XP_063117502.1 neurexin-3 isoform X10
XM_063261445.1 → XP_063117515.1 neurexin-3 isoform X26
XM_063261429.1 → XP_063117499.1 neurexin-3 isoform X5
XM_039111631.2 → XP_038967559.1 neurexin-3 isoform X3

UniProtKB/TrEMBL

A0A8I6GKL9

Conserved Domains (6) summary

smart00282
Location:282 → 413

LamG; Laminin G domain

cd00054
Location:647 → 680

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1610 → 1645

Syndecan; Syndecan domain

pfam02210
Location:899 → 1027

Laminin_G_2; Laminin G domain
XM_063261451.1 → XP_063117521.1 neurexin-3 isoform X34
XM_063261435.1 → XP_063117505.1 neurexin-3 isoform X13
XM_063261452.1 → XP_063117522.1 neurexin-3 isoform X35

Related

ENSRNOP00000087097.2, ENSRNOT00000097486.2
XM_063261455.1 → XP_063117525.1 neurexin-3 isoform X40
XM_063261439.1 → XP_063117509.1 neurexin-3 isoform X18
XM_063261456.1 → XP_063117526.1 neurexin-3 isoform X41
XM_063261430.1 → XP_063117500.1 neurexin-3 isoform X7
XM_063261436.1 → XP_063117506.1 neurexin-3 isoform X14
XM_039111657.2 → XP_038967585.1 neurexin-3 isoform X23

UniProtKB/TrEMBL

D3ZKS5

Conserved Domains (6) summary

smart00282
Location:282 → 413

LamG; Laminin G domain

cd00054
Location:647 → 680

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1393 → 1428

Syndecan; Syndecan domain

pfam02210
Location:899 → 1027

Laminin_G_2; Laminin G domain
XM_039111642.2 → XP_038967570.1 neurexin-3 isoform X15

UniProtKB/TrEMBL

D3ZKS5

Conserved Domains (6) summary

smart00282
Location:282 → 413

LamG; Laminin G domain

cd00054
Location:647 → 680

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1497 → 1532

Syndecan; Syndecan domain

pfam02210
Location:899 → 1027

Laminin_G_2; Laminin G domain
XM_063261443.1 → XP_063117513.1 neurexin-3 isoform X24
XM_063261457.1 → XP_063117527.1 neurexin-3 isoform X42
XM_039111643.2 → XP_038967571.1 neurexin-3 isoform X19

UniProtKB/TrEMBL

D3ZKS5

Conserved Domains (6) summary

smart00282
Location:282 → 413

LamG; Laminin G domain

cd00054
Location:647 → 680

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1467 → 1502

Syndecan; Syndecan domain

pfam02210
Location:899 → 1027

Laminin_G_2; Laminin G domain
XM_063261458.1 → XP_063117528.1 neurexin-3 isoform X43
XM_039111634.2 → XP_038967562.1 neurexin-3 isoform X8

UniProtKB/TrEMBL

A0A8I6GKL9

Related

ENSRNOP00000094179.1, ENSRNOT00000113245.2

Conserved Domains (6) summary

smart00282
Location:282 → 413

LamG; Laminin G domain

cd00054
Location:647 → 680

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1601 → 1636

Syndecan; Syndecan domain

pfam02210
Location:890 → 1018

Laminin_G_2; Laminin G domain
XM_063261437.1 → XP_063117507.1 neurexin-3 isoform X16
XM_063261444.1 → XP_063117514.1 neurexin-3 isoform X25
XM_063261438.1 → XP_063117508.1 neurexin-3 isoform X17
XM_039111662.2 → XP_038967590.1 neurexin-3 isoform X47

UniProtKB/TrEMBL

D3ZKS5

Conserved Domains (6) summary

smart00282
Location:282 → 413

LamG; Laminin G domain

cd00054
Location:647 → 680

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1351 → 1386

Syndecan; Syndecan domain

pfam02210
Location:890 → 1018

Laminin_G_2; Laminin G domain
XM_039111633.2 → XP_038967561.1 neurexin-3 isoform X6

UniProtKB/TrEMBL

A0A8I6GKL9

Conserved Domains (6) summary

smart00282
Location:266 → 405

LamG; Laminin G domain

cd00054
Location:639 → 672

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1602 → 1637

Syndecan; Syndecan domain

pfam02210
Location:891 → 1019

Laminin_G_2; Laminin G domain
XM_039111658.2 → XP_038967586.1 neurexin-3 isoform X39

UniProtKB/TrEMBL

A0A8I6GKC4

Conserved Domains (6) summary

smart00282
Location:266 → 405

LamG; Laminin G domain

cd00054
Location:639 → 672

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1376 → 1411

Syndecan; Syndecan domain

pfam02210
Location:882 → 1010

Laminin_G_2; Laminin G domain
XM_063261449.1 → XP_063117519.1 neurexin-3 isoform X32
XM_063261450.1 → XP_063117520.1 neurexin-3 isoform X33
XM_063261453.1 → XP_063117523.1 neurexin-3 isoform X37
XM_063261454.1 → XP_063117524.1 neurexin-3 isoform X38
XM_039111659.2 → XP_038967587.1 neurexin-3 isoform X44

UniProtKB/TrEMBL

A0A8I6GKC4

Conserved Domains (6) summary

smart00282
Location:266 → 397

LamG; Laminin G domain

cd00054
Location:631 → 664

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1338 → 1373

Syndecan; Syndecan domain

pfam02210
Location:874 → 1002

Laminin_G_2; Laminin G domain
XM_039111660.2 → XP_038967588.1 neurexin-3 isoform X45

UniProtKB/TrEMBL

A0A8I6GKC4

Conserved Domains (6) summary

smart00282
Location:266 → 397

LamG; Laminin G domain

cd00054
Location:631 → 664

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00110
Location:27 → 181

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam00008
Location:202 → 231

EGF; EGF-like domain

pfam01034
Location:1335 → 1370

Syndecan; Syndecan domain

pfam02210
Location:874 → 1002

Laminin_G_2; Laminin G domain
XM_063261424.1 → XP_063117494.1 neurexin-3 isoform X1
XM_063261426.1 → XP_063117496.1 neurexin-3 isoform X1
XM_063261448.1 → XP_063117518.1 neurexin-3 isoform X29
XM_039111663.2 → XP_038967591.1 neurexin-3 isoform X31

Conserved Domains (2) summary

cd00110
Location:86 → 235

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam01034
Location:355 → 390

Syndecan; Syndecan domain
XM_008764733.4 → XP_008762955.2 neurexin-3 isoform X30

Conserved Domains (2) summary

cd00110
Location:86 → 265

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

pfam01034
Location:385 → 420

Syndecan; Syndecan domain