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CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 [ Gallus gallus (chicken) ]

Gene ID: 107054381, updated on 17-Aug-2024

Summary

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Symbol
CELSR3provided by CGNC
Full Name
cadherin EGF LAG seven-pass G-type receptor 3provided by CGNC
Primary source
CGNC:50137
See related
Ensembl:ENSGALG00010027145
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See CELSR3 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
36
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 12 NC_052543.1 (9206582..9231570)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 12 NC_052584.1 (9234250..9259236)

Chromosome 12 - NC_052543.1Genomic Context describing neighboring genes Neighboring gene inositol hexakisphosphate kinase 2 Neighboring gene NCK interacting protein with SH3 domain Neighboring gene solute carrier family 26 member 6 Neighboring gene ubiquinol-cytochrome c reductase core protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression of multiple cadherins and catenins in the chick optic tectum. Miskevich F, et al. Mol Cell Neurosci, 1998 Nov. PMID 9828089

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cadherin EGF LAG seven-pass G-type receptor 3
Names
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052543.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    9206582..9231570
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025154618.3 → XP_025010386.2  cadherin EGF LAG seven-pass G-type receptor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8V1A2N2
    Conserved Domains (9) summary
    smart00303
    Location:2356 → 2407
    GPS; G-protein-coupled receptor proteolytic site domain
    cd11304
    Location:430 → 527
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00180
    Location:1842 → 1887
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00054
    Location:1205 → 1240
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:1285 → 1468
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00185
    Location:1826 → 1861
    TNFRSF; CRD2 [structural motif]
    cd15993
    Location:2416 → 2669
    7tmB2_CELSR3; Cadherin EGF LAG seven-pass G-type receptor 3, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    cl02422
    Location:2031 → 2068
    HRM; Hormone receptor domain
    cl22855
    Location:1775 → 1866
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  2. XM_025154619.3 → XP_025010387.2  cadherin EGF LAG seven-pass G-type receptor 3 isoform X2

    UniProtKB/TrEMBL
    A0A8V1A2N2
    Related
    ENSGALP00010040140.1, ENSGALT00010065874.1
    Conserved Domains (9) summary
    smart00303
    Location:2245 → 2296
    GPS; G-protein-coupled receptor proteolytic site domain
    cd11304
    Location:430 → 527
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00008
    Location:1891 → 1957
    HormR; Domain present in hormone receptors
    smart00180
    Location:1842 → 1887
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00054
    Location:1205 → 1240
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:1285 → 1468
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00185
    Location:1775 → 1824
    TNFRSF; CRD1 [structural motif]
    cd15993
    Location:2305 → 2558
    7tmB2_CELSR3; Cadherin EGF LAG seven-pass G-type receptor 3, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    cl22855
    Location:1775 → 1866
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  3. XM_025154620.3 → XP_025010388.2  cadherin EGF LAG seven-pass G-type receptor 3 isoform X3

    UniProtKB/TrEMBL
    A0A8V1A2N2
    Related
    ENSGALP00010040143.1, ENSGALT00010065877.1
    Conserved Domains (9) summary
    smart00303
    Location:2240 → 2291
    GPS; G-protein-coupled receptor proteolytic site domain
    cd11304
    Location:430 → 527
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00008
    Location:1891 → 1952
    HormR; Domain present in hormone receptors
    smart00180
    Location:1842 → 1887
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00054
    Location:1205 → 1240
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:1285 → 1468
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00185
    Location:1775 → 1824
    TNFRSF; CRD1 [structural motif]
    cd15993
    Location:2300 → 2553
    7tmB2_CELSR3; Cadherin EGF LAG seven-pass G-type receptor 3, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    cl22855
    Location:1775 → 1866
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

RNA

  1. XR_005839216.2 RNA Sequence

    Related
    ENSGALT00010065867.1

  2. XR_005839215.2 RNA Sequence

    Related
    ENSGALT00010065862.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052584.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    9234250..9259236
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040682295.2 → XP_040538229.1  cadherin EGF LAG seven-pass G-type receptor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8V1A2N2
    Conserved Domains (9) summary
    smart00303
    Location:2356 → 2407
    GPS; G-protein-coupled receptor proteolytic site domain
    cd11304
    Location:430 → 527
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00180
    Location:1842 → 1887
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00054
    Location:1205 → 1240
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:1285 → 1468
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00185
    Location:1775 → 1824
    TNFRSF; CRD1 [structural motif]
    cd15993
    Location:2416 → 2669
    7tmB2_CELSR3; Cadherin EGF LAG seven-pass G-type receptor 3, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    cl02422
    Location:2031 → 2068
    HRM; Hormone receptor domain
    cl22855
    Location:1775 → 1866
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  2. XM_040682296.2 → XP_040538230.1  cadherin EGF LAG seven-pass G-type receptor 3 isoform X2

    UniProtKB/TrEMBL
    A0A8V1A2N2
    Conserved Domains (9) summary
    smart00303
    Location:2245 → 2296
    GPS; G-protein-coupled receptor proteolytic site domain
    cd11304
    Location:430 → 527
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00008
    Location:1891 → 1957
    HormR; Domain present in hormone receptors
    smart00180
    Location:1842 → 1887
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00054
    Location:1205 → 1240
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:1285 → 1468
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00185
    Location:1775 → 1824
    TNFRSF; CRD1 [structural motif]
    cd15993
    Location:2305 → 2558
    7tmB2_CELSR3; Cadherin EGF LAG seven-pass G-type receptor 3, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    cl22855
    Location:1775 → 1866
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  3. XM_040682297.2 → XP_040538231.1  cadherin EGF LAG seven-pass G-type receptor 3 isoform X3

    UniProtKB/TrEMBL
    A0A8V1A2N2
    Conserved Domains (9) summary
    smart00303
    Location:2240 → 2291
    GPS; G-protein-coupled receptor proteolytic site domain
    cd11304
    Location:430 → 527
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00008
    Location:1891 → 1952
    HormR; Domain present in hormone receptors
    smart00180
    Location:1842 → 1887
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00054
    Location:1205 → 1240
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:1285 → 1468
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00185
    Location:1775 → 1824
    TNFRSF; CRD1 [structural motif]
    cd15993
    Location:2300 → 2553
    7tmB2_CELSR3; Cadherin EGF LAG seven-pass G-type receptor 3, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    cl22855
    Location:1775 → 1866
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

RNA

  1. XR_005853695.2 RNA Sequence

  2. XR_005853694.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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