U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CDR1-AS CDR1 antisense RNA [ Homo sapiens (human) ]

Gene ID: 103611090, updated on 26-Feb-2024

Summary

Go to the top of the page Help
Official Symbol
CDR1-ASprovided by HGNC
Official Full Name
CDR1 antisense RNAprovided by HGNC
Primary source
HGNC:HGNC:48926
See related
MIM:300898
Gene type
ncRNA
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CIRS7; CDR1as; ciRS-7; CDR1NAT
Summary
This gene represents naturally-occurring RNAs transcribed in antisense to CDR1 (cerebellar degeneration-related protein 1, 34kDa; GeneID:1038), some of which may be circular rather than linear. The circular RNA produced by this locus acts as an miRNA sponge, preventing the miRNA from interacting with target transcripts. No RefSeq transcript is created for the circular RNA. [provided by RefSeq, Feb 2024]
Annotation information
not in current annotation release
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
Xq27.1

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. CircRNA CDR1as: a novel diagnostic and prognostic biomarker for gastric cancer. Li R, et al. Biomarkers, 2023 Dec. PMID 37128800
  2. ciRS-7 is a prognostic biomarker and potential gene therapy target for renal cell carcinoma. Mao W, et al. Mol Cancer, 2021 Nov 5. PMID 34740354, Free PMC Article
  3. Circulating expression levels of CircHIPK3 and CDR1as circular-RNAs in type 2 diabetes patients. Rezaeinejad F, et al. Mol Biol Rep, 2022 Jan. PMID 34731367
  4. UVB-Induced ciRS-7 Activates Melanogenesis by Paracrine Effects. Ouyang Y, et al. DNA Cell Biol, 2021 Mar. PMID 33687273
  5. CircRNA ciRS-7: a Novel Oncogene in Multiple Cancers. Chen J, et al. Int J Biol Sci, 2021. PMID 33390857, Free PMC Article

See all (51) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Exosomes From IgE-Stimulated Mast Cells Aggravate Asthma-Mediated Atherosclerosis Through circRNA CDR1as-Mediated Endothelial Cell Dysfunction in Mice.
    Title: Exosomes From IgE-Stimulated Mast Cells Aggravate Asthma-Mediated Atherosclerosis Through circRNA CDR1as-Mediated Endothelial Cell Dysfunction in Mice.
  2. Circular RNA Cdr1as inhibits proliferation and delays injury-induced regeneration of the intestinal epithelium.
    Title: Circular RNA Cdr1as inhibits proliferation and delays injury-induced regeneration of the intestinal epithelium.
  3. CDR1-AS is an oncogene that promotes laryngeal squamous cell carcinoma progression by regulating miR-7 signals
    Title: CDR1as is overexpressed in laryngeal squamous cell carcinoma to promote the tumour's progression via miR-7 signals.
  4. IGF2BP3-mediated melanoma invasion and metastasis is driven by epigenetic silencing of CDR1-AS.
    Title: Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis.
  5. Circular RNA CDR1-AS Exerts Oncogenic Properties Partially through Regulating MicroRNA 641 in Cholangiocarcinoma.
    Title: Circular RNA CDR1as Exerts Oncogenic Properties Partially through Regulating MicroRNA 641 in Cholangiocarcinoma.
  6. CircRNA CDR1as: a novel diagnostic and prognostic biomarker for gastric cancer.
    Title: CircRNA CDR1as: a novel diagnostic and prognostic biomarker for gastric cancer.
  7. Circular RNA ciRS-7 affects the propagation of Cryptosporidium parvum in HCT-8 cells via regulating miR-135a-5p/stat1 axis.
    Title: Circular RNA ciRS-7 affects the propagation of Cryptosporidium parvum in HCT-8 cells via regulating miR-135a-5p/stat1 axis.
  8. Circulating expression levels of CircHIPK3 and CDR1as circular-RNAs in type 2 diabetes patients.
    Title: Circulating expression levels of CircHIPK3 and CDR1as circular-RNAs in type 2 diabetes patients.
  9. ciRS-7 is a prognostic biomarker and potential gene therapy target for renal cell carcinoma.
    Title: ciRS-7 is a prognostic biomarker and potential gene therapy target for renal cell carcinoma.
  10. CircRNA ciRS-7: a Novel Oncogene in Multiple Cancers.
    Title: CircRNA ciRS-7: a Novel Oncogene in Multiple Cancers.
Submit: New GeneRIF Correction See all GeneRIFs (43)

General gene information

Go to the top of the page Help

Other Names

  • CDR1 natural antisense transcript
  • circular RNA sponge for miR-7

Clone Names

  • FLJ30359, FLJ37221

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials