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MIR6778 microRNA 6778 [ Homo sapiens (human) ]

Gene ID: 102466733, updated on 17-Sep-2024

Summary

Official Symbol
MIR6778provided by HGNC
Official Full Name
microRNA 6778provided by HGNC
Primary source
HGNC:HGNC:50183
See related
Ensembl:ENSG00000283772 miRBase:MI0022623; AllianceGenome:HGNC:50183
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
hsa-mir-6778
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR6778 in Genome Data Viewer
Location:
17p11.2
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (18340814..18340886, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (18287619..18287691, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (18244128..18244200, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene DNA topoisomerase III alpha Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:18217357-18217880 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11836 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:18218405-18218928 Neighboring gene ribosomal protein L21 pseudogene 121 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:18224803-18224995 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:18225507-18226008 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:18226009-18226508 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8275 Neighboring gene SMCR8-C9orf72 complex subunit Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:18233711-18234211 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:18235020-18235826 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:18235827-18236631 Neighboring gene serine hydroxymethyltransferase 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8276 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:18276669-18277169 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:18283393-18283894 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:18285838-18286409 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:18286410-18286980 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:18292166-18292878 Neighboring gene envoplakin like Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:18302365-18302865 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:18303020-18303520 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:18303521-18304021 Neighboring gene TBC1 domain family member 3 pseudogene 4

Genomic regions, transcripts, and products

Bibliography

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_106836.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC127537
    Related
    ENST00000617912.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    18340814..18340886 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_017363819.1 Reference GRCh38.p14 PATCHES

    Range
    101188..101260 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    18287619..18287691 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)