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Sipa1l1 signal induced proliferation associated 1 like 1 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101723757, updated on 8-Mar-2024

Summary

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Gene symbol
Sipa1l1
Gene description
signal induced proliferation associated 1 like 1
See related
Ensembl:ENSHGLG00000011768
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Sipa1l1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624734.1 (29612867..29998602, complement)

NW_004624734.1Genomic Context describing neighboring genes Neighboring gene glomulin pseudogene Neighboring gene uncharacterized LOC110346327 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene uncharacterized LOC110346821

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624734 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of small GTPase mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal-induced proliferation-associated 1-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624734.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    29612867..29998602 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013067449.2 → XP_012922903.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_012922903.1

    Related
    ENSHGLP00000016434.1, ENSHGLT00000016603.1
    Conserved Domains (4) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1736 → 1791
    ZapB; Cell division protein ZapB
    pfam11881
    Location:1503 → 1748
    SPAR_C; C-terminal domain of SPAR protein

  2. XM_004837281.3 → XP_004837338.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_004837338.1

    Conserved Domains (4) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1736 → 1791
    ZapB; Cell division protein ZapB
    pfam11881
    Location:1503 → 1748
    SPAR_C; C-terminal domain of SPAR protein

  3. XM_021247052.1 → XP_021102711.1  signal-induced proliferation-associated 1-like protein 1 isoform X7

    Conserved Domains (5) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1671 → 1726
    ZapB; Cell division protein ZapB
    pfam11881
    Location:1438 → 1683
    SPAR_C; C-terminal domain of SPAR protein
    pfam12004
    Location:1180 → 1392
    DUF3498; Domain of unknown function (DUF3498)

  4. XM_004837285.3 → XP_004837342.1  signal-induced proliferation-associated 1-like protein 1 isoform X4

    Related
    ENSHGLP00000016436.1, ENSHGLT00000016605.1
    Conserved Domains (4) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1714 → 1769
    DUF904; Protein of unknown function (DUF904)
    pfam11881
    Location:1482 → 1726
    SPAR_C; C-terminal domain of SPAR protein

  5. XM_013067452.2 → XP_012922906.1  signal-induced proliferation-associated 1-like protein 1 isoform X3

    Conserved Domains (4) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1715 → 1770
    DUF904; Protein of unknown function (DUF904)
    pfam11881
    Location:1482 → 1727
    SPAR_C; C-terminal domain of SPAR protein

  6. XM_021247041.1 → XP_021102700.1  signal-induced proliferation-associated 1-like protein 1 isoform X5

    Conserved Domains (5) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1692 → 1747
    ZapB; Cell division protein ZapB
    pfam11881
    Location:1459 → 1704
    SPAR_C; C-terminal domain of SPAR protein
    cl02571
    Location:1166 → 1412
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  7. XM_004837287.3 → XP_004837344.1  signal-induced proliferation-associated 1-like protein 1 isoform X6

    Conserved Domains (4) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1689 → 1744
    DUF904; Protein of unknown function (DUF904)
    pfam11881
    Location:1456 → 1701
    SPAR_C; C-terminal domain of SPAR protein

  8. XM_004837283.3 → XP_004837340.1  signal-induced proliferation-associated 1-like protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A0P6J3C0
    Conserved Domains (4) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1735 → 1790
    DUF904; Protein of unknown function (DUF904)
    pfam11881
    Location:1503 → 1747
    SPAR_C; C-terminal domain of SPAR protein

  9. XM_004837278.3 → XP_004837335.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_004837335.1

    Conserved Domains (4) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1736 → 1791
    ZapB; Cell division protein ZapB
    pfam11881
    Location:1503 → 1748
    SPAR_C; C-terminal domain of SPAR protein

  10. XM_013067445.2 → XP_012922899.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_012922899.1

    Related
    ENSHGLP00000016433.1, ENSHGLT00000016602.1
    Conserved Domains (4) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1736 → 1791
    ZapB; Cell division protein ZapB
    pfam11881
    Location:1503 → 1748
    SPAR_C; C-terminal domain of SPAR protein

  11. XM_004837279.3 → XP_004837336.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_004837336.1

    Conserved Domains (4) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1736 → 1791
    ZapB; Cell division protein ZapB
    pfam11881
    Location:1503 → 1748
    SPAR_C; C-terminal domain of SPAR protein

  12. XM_021246997.1 → XP_021102656.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    Conserved Domains (4) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1736 → 1791
    ZapB; Cell division protein ZapB
    pfam11881
    Location:1503 → 1748
    SPAR_C; C-terminal domain of SPAR protein

  13. XM_021247003.1 → XP_021102662.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    Conserved Domains (4) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1736 → 1791
    ZapB; Cell division protein ZapB
    pfam11881
    Location:1503 → 1748
    SPAR_C; C-terminal domain of SPAR protein

  14. XM_004837282.3 → XP_004837339.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_004837339.1

    Related
    ENSHGLP00000016435.1, ENSHGLT00000016604.1
    Conserved Domains (4) summary
    cd00992
    Location:953 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629 → 809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:1736 → 1791
    ZapB; Cell division protein ZapB
    pfam11881
    Location:1503 → 1748
    SPAR_C; C-terminal domain of SPAR protein
Nucleotide Protein
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